Protein Alignment ROGDI and H14A12.3

DIOPT Version :10

• Sequence 1: XP_006721010.1
• Gene: ROGDI / 79641
• HGNCID: 29478
• Length: 294
• Species: Homo sapiens
• Sequence 2: NP_498641.1
• Gene: H14A12.3 / 176058
• WormBaseID: WBGene00019196
• Length: 292
• Species: Caenorhabditis elegans
• Alignment Length: 289
• Identity: 71/289 - (24%)
• Similarity: 118/289 - (40%)
• Gaps: 56/289 - (19%)

Human    21 WLLHDEVHAVLKQLQDILKEASLRFTLPGSGTE--------GPAKQENFILGSCGTDQVKGVLTL 77
            |:...:|...|:...:.||...:...|.....|        |..::...:..:..:|.:|..:||
 Worm    38 WIQRKDVDTTLRSALEHLKACCIVLNLSAKCDERLNVAVSHGTTEKYQLMSRTGSSDNLKAAVTL 102

Human    78 QGDALSQADVNLKMPRNNQLLHFAFRE-DKQWKLQQIQDARNHVSQAIYLLT------------- 128
            ..|.:.||:|.:|.|:.....:.|..: |.||||||:||..||:|:....|.
 Worm   103 LDDNVIQAEVTVKYPKAGGGYYRAVAQPDVQWKLQQLQDLGNHISRVTITLCDLQHEVNLLKGDG 167

Human   129 SRDQSYQFKTGAEVLKLMDAVMLQLTRARNRLTTPATLTLPEIAASGLTRMFAPALPSDLLVNVY 193
            .|| ::...|||.:|:.:...|.:::.|||.:..|...:|.|:.....||.|.|.||.|.|::.|
 Worm   168 ERD-AFTLATGARILEELKLTMNEISLARNSIMLPRKRSLLELCYFPPTRKFVPPLPQDQLISFY 231

Human   194 INLNKLCLTVYQLHALQPNSTKNFRPAGGAVLHSPGAMLDPLTAHSEWGSQRLEVSHVHKVECVI 258
            |:..:|....||                          :.|.|.|.:..|       |...|..:
 Worm   232 ISCCRLVCASYQ--------------------------MVPKTVHPQGLS-------VFMAESQL 263

Human   259 PWLNDALVYFTVSLQLCQQLKDKISVFSS 287
            |.|:|.:.:....:.:.|:|.:.:|...|
 Worm   264 PHLDDVIKHLNTVMAILQKLINYLSATMS 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ROGDI	XP_006721010.1	Rogdi_lz	18..283	CDD:463031	69/283 (24%)
H14A12.3	NP_498641.1	Rogdi_lz	90..>272	CDD:463031	59/215 (27%)