Protein Alignment MUL1 and Mul1

DIOPT Version :10

• Sequence 1: NP_078820.2
• Gene: MUL1 / 79594
• HGNCID: 25762
• Length: 352
• Species: Homo sapiens
• Sequence 2: NP_647847.1
• Gene: Mul1 / 38472
• FlyBaseID: FBgn0035483
• Length: 338
• Species: Drosophila melanogaster
• Alignment Length: 336
• Identity: 106/336 - (31%)
• Similarity: 180/336 - (53%)
• Gaps: 26/336 - (7%)

Human    13 ILLGTTSVVTAALYSVYRQKARVSQELKGAKKVHLGEDLKSILSEAPGKCVPYAVIEGAVRSVKE 77
            ::||    :.|..|..|::.|:|   ||.|.:.::..||||::.....|.:|||||.|.|..:..
  Fly    15 LILG----LCAREYVHYKRTAKV---LKAAPQYNIDGDLKSVVERQRDKKIPYAVIRGTVTPIGV 72

Human    78 TLNSQFVENCKGVIQRLTLQEHKMVWNRTTHLWNDCSKIIHQRTNTVPFDLVPHEDGVDVAVRVL 142
            .|.|..|.:..||:|.:.|.||: |.......|.:..|::|:..|.:||:|.....||:    ::
  Fly    73 PLRSSLVPSVSGVLQIVKLHEHR-VTRGFAGFWTEQHKLLHESANEMPFELRNQSHGVE----IV 132

Human   143 KPLDSVDLGLETVYEKFHPSIQSFTDVIGHYISGERPKGIQETEEMLKVGATLTGVGELVLDNNS 207
            ..|.:..|.::.||:.:.||..|..|.:..:.||.|.:|:|.|||:|:.|:.||.:|||.||.::
  Fly   133 DALSAAVLDVDVVYDNYEPSNLSLFDHVFGFFSGVRQRGLQTTEEVLREGSFLTAIGELELDGDT 197

Human   208 VRLQPPKQGMQYYLSSQDFDSLLQRQESSVRLWKVLALVFGFATCATL-----FFILRKQYLQRQ 267
            :|:||..:| ..:|::....:|::|.|.: :...:|.||    .|:|:     .||.:|.|.:|:
  Fly   198 LRMQPSNEG-PLFLTTATKSTLIKRFEDA-KTTTILKLV----VCSTISAILVAFIAKKLYRKRK 256

Human   268 ERLRLKQMQEEFQEHEAQLLSRAKPEDRESLKSACVVCLSSFKSCVFLECGHVCSCTECYRALPE 332
            :.....:::|.......:..:|::|... |....||||.::.|..:.|.|||||.|.:|.:.:
  Fly   257 QEREEAKIRERLDTERRERRARSRPHTL-SQDQLCVVCSTNPKEIILLPCGHVCLCEDCAQKI-- 318

Human   333 PKKCPICRQAI 343
            ...||:||.:|
  Fly   319 SVTCPVCRGSI 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MUL1	NP_078820.2	GIDE	97..253	CDD:403620	48/155 (31%)
		mRING-HC-C3HC5_MAPL	299..350	CDD:438310	18/45 (40%)
Mul1	NP_647847.1	GIDE	89..243	CDD:403620	51/164 (31%)
		mRING-HC-C3HC5_CGRF1-like	288..326	CDD:438311	15/39 (38%)