DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RNF128 and ASR1

DIOPT Version :9

Sequence 1:	NP_919445.1	Gene:	RNF128 / 79589	HGNCID:	21153	Length:	428	Species:	Homo sapiens
Sequence 2:	NP_015418.2	Gene:	ASR1 / 856208	SGDID:	S000006297	Length:	288	Species:	Saccharomyces cerevisiae

Alignment Length:	121	Identity:	26/121 - (21%)
Similarity:	50/121 - (41%)	Gaps:	23/121 - (19%)

- Green bases have known domain annotations that are detailed below.

Human   275 DSCAVCIELYKPNDLVRIL-TCNHIFHKTCVDPWLLEHR-----TCPMCKCDILKALGIEVDVED 333
            :.|.:|:...:..:....| .|.|.||..|:..|   |:     .||:|:   :::..:||....
Yeast     2 EECPICLADDQEGEQFGCLNVCGHKFHLNCIREW---HKYSINLKCPICR---VESTHLEVGEGQ 60

Human   334 GSVSLQVPVSNEISNS-----ASSHEEDNRSETASSGYASVQGTDEPPLEEHVQST 384
            .::|:.:.:...|.|:     |.:..|.|..:|..      |..:...|.|.::.|
Yeast    61 HALSINLKMGFMIKNAIDYVGAETTNERNEDDTGE------QDQEIEFLSERLRGT 110

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RNF128	NP_919445.1	PA_GRAIL_like	48..193	CDD:239037
		RING-H2_RNF128_like	275..323	CDD:319716	13/53 (25%)
		RING-H2 finger (C3H2C3-type)	277..317	CDD:319716	12/45 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	346..428		10/44 (23%)
ASR1	NP_015418.2	RING-H2	4..48	CDD:319362	12/46 (26%)
ASR1	NP_015418.2	PHD	121..167	CDD:214584
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910