Protein Alignment CORO7 and Coro7

DIOPT Version :10

• Sequence 1: NP_078811.3
• Gene: CORO7 / 79585
• HGNCID: 26161
• Length: 925
• Species: Homo sapiens
• Sequence 2: NP_084481.3
• Gene: Coro7 / 78885
• MGIID: 1926135
• Length: 922
• Species: Mus musculus
• Alignment Length: 925
• Identity: 798/925 - (86%)
• Similarity: 845/925 - (91%)
• Gaps: 3/925 - (0%)

Human     1 MNRFRVSKFRHTEARPPRRESWISDIRAGTAPSCRNHIKSSCSLIAFNSDRPGVLGIVPLQGQGE 65
            |:||:||||||.||||.|||:|||||||.|.|:|.|||||||||||||||||||||::.|:|..|
Mouse     1 MSRFKVSKFRHMEARPSRREAWISDIRAVTTPTCGNHIKSSCSLIAFNSDRPGVLGVISLEGHEE 65

Human    66 DKRRVAHLGCHSDLVTDLDFSPFDDFLLATGSADRTVKLWRLPGPGQALPSAPGVVLGPEDLPVE 130
            :||.|.:||||||||||||||||||||||:||||||:|||||.|.|:||||.||||||||:||||
Mouse    66 NKRHVTYLGCHSDLVTDLDFSPFDDFLLASGSADRTIKLWRLSGTGEALPSVPGVVLGPEELPVE 130

Human   131 VLQFHPTSDGILVSAAGTTVKVWDAAKQQPLTELAAHGDLVQSAVWSRDGALVGTACKDKQLRIF 195
            |||||||.||:|||.||.||||||.|||||||||.||.|||||||||||||:|||||||||||||
Mouse   131 VLQFHPTVDGVLVSTAGKTVKVWDVAKQQPLTELEAHKDLVQSAVWSRDGAIVGTACKDKQLRIF 195

Human   196 DPRTKPRASQSTQAHENSRDSRLAWMGTWEHLVSTGFNQMREREVKLWDTRFFSSALASLTLDTS 260
            |||.:.:||||||||||:||.||||.|..|||||||||||||||.||||||.|||||||:|||||
Mouse   196 DPRARTQASQSTQAHENNRDIRLAWTGIQEHLVSTGFNQMREREAKLWDTRLFSSALASVTLDTS 260

Human   261 LGCLVPLLDPDSGLLVLAGKGERQLYCYEVVPQQPALSPVTQCVLESVLRGAALVPRQALAVMSC 325
            .|.|:|||||||||||||||||.|||||||.||||||||||||:||:||||||||||:|||||||
Mouse   261 PGPLIPLLDPDSGLLVLAGKGENQLYCYEVTPQQPALSPVTQCILENVLRGAALVPRRALAVMSC 325

Human   326 EVLRVLQLSDTAIVPIGYHVPRKAVEFHEDLFPDTAGCVPATDPHSWWAGDNQQVQKVSLNPACR 390
            |||:|||||||||:||.:|||||||||||||||||||.|||:|.|.|||||||||||||||||.|
Mouse   326 EVLQVLQLSDTAIIPISHHVPRKAVEFHEDLFPDTAGSVPASDAHMWWAGDNQQVQKVSLNPARR 390

Human   391 PHPSFTSCLVPPAEPLPDTAQPAVMETPVGDADASEGFSSPPSSLTSPSTPSSLGPSLSSTSGIG 455
            |||.|||.|||..||.||..|||  |.|..|.|.|||||| ||||.|||||||||||||||||||
Mouse   391 PHPCFTSSLVPTMEPAPDMVQPA--EMPRADTDLSEGFSS-PSSLMSPSTPSSLGPSLSSTSGIG 452

Human   456 TSPSLRSLQSLLGPSSKFRHAQGTVLHRDSHITNLKGLNLTTPGESDGFCANKLRVAVPLLSSGG 520
            ||||.|||||||||||||||.||::|||||||||||||||||||||||||||:||||||||||||
Mouse   453 TSPSQRSLQSLLGPSSKFRHTQGSLLHRDSHITNLKGLNLTTPGESDGFCANRLRVAVPLLSSGG 517

Human   521 QVAVLELRKPGRLPDTALPTLQNGAAVTDLAWDPFDPHRLAVAGEDARIRLWRVPAEGLEEVLTT 585
            |||||||:||||||||||||||||.||.||.||||||||||||||||||||||||..|||.||||
Mouse   518 QVAVLELQKPGRLPDTALPTLQNGTAVMDLVWDPFDPHRLAVAGEDARIRLWRVPPGGLENVLTT 582

Human   586 PETVLTGHTEKICSLRFHPLAANVLASSSYDLTVRIWDLQAGADRLKLQGHQDQIFSLAWSPDGQ 650
            ||||||||||||.|||||||||:|||||||||||||||||.||:||||||||||||||||||||:
Mouse   583 PETVLTGHTEKIYSLRFHPLAADVLASSSYDLTVRIWDLQTGAERLKLQGHQDQIFSLAWSPDGK 647

Human   651 QLATVCKDGRVRVYRPRSGPEPLQEGPGPKGGRGARIVWVCDGRCLLVSGFDSQSERQLLLYEAE 715
            |||||||||.||||.|||.|.||||||||:|||||||||||||.|||||||||:|||||.||.|:
Mouse   648 QLATVCKDGHVRVYEPRSSPLPLQEGPGPEGGRGARIVWVCDGGCLLVSGFDSRSERQLQLYIAD 712

Human   716 ALAGGPLAVLGLDVAPSTLLPSYDPDTGLVLLTGKGDTRVFLYELLPESPFFLECNSFTSPDPHK 780
            |||.||.|:|||||||||||||||||||||||||||||||||||:|||:||||||||||||||||
Mouse   713 ALAQGPSALLGLDVAPSTLLPSYDPDTGLVLLTGKGDTRVFLYEVLPEAPFFLECNSFTSPDPHK 777

Human   781 GLVLLPKTECDVREVELMRCLRLRQSSLEPVAFRLPRVRKEFFQDDVFPDTAVIWEPVLSAEAWL 845
            |.|||||||||:::||..|||||||:|||||||||||||||||||||||||||.|||.|||:||.
Mouse   778 GFVLLPKTECDIQDVEFARCLRLRQTSLEPVAFRLPRVRKEFFQDDVFPDTAVTWEPALSAKAWF 842

Human   846 QGANGQPWLLSLQPPDMSPVSQAPREAPARRAPSSAQYLEEKSDQQKKEELLNAMVAKLGNREDP 910
            :||||||.|||||||.|:||||||||.||||||||||||||||||||||||||||||||||||||
Mouse   843 EGANGQPRLLSLQPPGMTPVSQAPREVPARRAPSSAQYLEEKSDQQKKEELLNAMVAKLGNREDP 907

Human   911 LPQDSFEGVDEDEWD 925
            |||||||||||||||
Mouse   908 LPQDSFEGVDEDEWD 922

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CORO7	NP_078811.3	WD40	6..428	CDD:475233	346/421 (82%)
		WD 1	75..115		34/39 (87%)
		WD40 repeat	81..124	CDD:293791	36/42 (86%)
		WD 2	124..163		32/38 (84%)
		WD40 repeat	129..165	CDD:293791	30/35 (86%)
		WD 3	166..205		32/38 (84%)
		WD40 repeat	172..208	CDD:293791	30/35 (86%)
		WD 4	209..253		36/43 (84%)
		WD40 repeat	215..256	CDD:293791	34/40 (85%)
		WD40 repeat	263..302	CDD:293791	34/38 (89%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	419..461		35/41 (85%)
		WD40	471..880	CDD:475233	361/408 (88%)
		WD40 repeat	504..540	CDD:293791	33/35 (94%)
		WD 5	542..582		34/39 (87%)
		WD40 repeat	547..591	CDD:293791	38/43 (88%)
		WD 6	592..632		35/39 (90%)
		WD40 repeat	598..634	CDD:293791	31/35 (89%)
		WD 7	635..674		33/38 (87%)
		WD40 repeat	640..677	CDD:293791	31/36 (86%)
		WD 8	728..768		37/39 (95%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	858..925		63/66 (95%)
Coro7	NP_084481.3	WD40	6..>379	CDD:475233	312/372 (84%)
		WD40 repeat	42..73	CDD:293791	21/30 (70%)
		WD 1	75..115		34/39 (87%)
		WD40 repeat	81..124	CDD:293791	36/42 (86%)
		WD 2	124..163		32/38 (84%)
		WD40 repeat	129..165	CDD:293791	30/35 (86%)
		WD 3	166..205		32/38 (84%)
		WD40 repeat	172..208	CDD:293791	30/35 (86%)
		WD 4	209..253		36/43 (84%)
		WD40 repeat	215..256	CDD:293791	34/40 (85%)
		WD40 repeat	264..302	CDD:293791	34/37 (92%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	419..467		43/48 (90%)
		WD40	468..877	CDD:475233	361/408 (88%)
		WD 5	539..581		35/41 (85%)
		WD40 repeat	545..589	CDD:293791	38/43 (88%)
		WD 6	589..629		35/39 (90%)
		WD40 repeat	594..631	CDD:293791	32/36 (89%)
		WD 7	632..671		33/38 (87%)
		WD40 repeat	638..674	CDD:293791	30/35 (86%)
		WD40 repeat	681..722	CDD:293791	33/40 (83%)
		WD 8	725..765		37/39 (95%)
		WD40 repeat	730..773	CDD:293791	40/42 (95%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	858..922		60/63 (95%)