Protein Alignment CORO7 and Coro7

DIOPT Version :10

• Sequence 1: NP_078811.3
• Gene: CORO7 / 79585
• HGNCID: 26161
• Length: 925
• Species: Homo sapiens
• Sequence 2: NP_001178568.1
• Gene: Coro7 / 192276
• RGDID: 621591
• Length: 922
• Species: Rattus norvegicus
• Alignment Length: 925
• Identity: 780/925 - (84%)
• Similarity: 839/925 - (90%)
• Gaps: 3/925 - (0%)

Human     1 MNRFRVSKFRHTEARPPRRESWISDIRAGTAPSCRNHIKSSCSLIAFNSDRPGVLGIVPLQGQGE 65
            ||||:.|||||.||||.|||:|||||||||..:|.||||||||||||||||||||||:.|:|..|
  Rat     1 MNRFKASKFRHMEARPSRREAWISDIRAGTTATCGNHIKSSCSLIAFNSDRPGVLGIISLEGHEE 65

Human    66 DKRRVAHLGCHSDLVTDLDFSPFDDFLLATGSADRTVKLWRLPGPGQALPSAPGVVLGPEDLPVE 130
            :||.|.:||||||||||||||||||||||:||||||:|||||...|:||||.||||||||:|||:
  Rat    66 NKRHVTYLGCHSDLVTDLDFSPFDDFLLASGSADRTIKLWRLSSTGEALPSVPGVVLGPEELPVD 130

Human   131 VLQFHPTSDGILVSAAGTTVKVWDAAKQQPLTELAAHGDLVQSAVWSRDGALVGTACKDKQLRIF 195
            |||||||:||:|||.||.||||||.||||.||||.||.|||||||||||||.|||||||||||||
  Rat   131 VLQFHPTADGVLVSTAGRTVKVWDVAKQQHLTELEAHKDLVQSAVWSRDGATVGTACKDKQLRIF 195

Human   196 DPRTKPRASQSTQAHENSRDSRLAWMGTWEHLVSTGFNQMREREVKLWDTRFFSSALASLTLDTS 260
            |||.:.:||||||||||:||.||||.|..|:|||||||||||||.||||||.|||||||:|||||
  Rat   196 DPRARAQASQSTQAHENNRDIRLAWTGIQEYLVSTGFNQMREREAKLWDTRVFSSALASITLDTS 260

Human   261 LGCLVPLLDPDSGLLVLAGKGERQLYCYEVVPQQPALSPVTQCVLESVLRGAALVPRQALAVMSC 325
            .|.|:|||||||||||||||||.|||||||.||||||||||||:||:.|||||||||||||||:|
  Rat   261 PGSLIPLLDPDSGLLVLAGKGENQLYCYEVTPQQPALSPVTQCILENALRGAALVPRQALAVMNC 325

Human   326 EVLRVLQLSDTAIVPIGYHVPRKAVEFHEDLFPDTAGCVPATDPHSWWAGDNQQVQKVSLNPACR 390
            |||:|||||||||:||.:.||||||||||||||||||.|||:|.|:|||||||||||||||||.|
  Rat   326 EVLQVLQLSDTAIIPISHRVPRKAVEFHEDLFPDTAGSVPASDAHTWWAGDNQQVQKVSLNPAHR 390

Human   391 PHPSFTSCLVPPAEPLPDTAQPAVMETPVGDADASEGFSSPPSSLTSPSTPSSLGPSLSSTSGIG 455
            |||.|||.|:|..||.|:..|||  |.|..|.:.|||||| ||||.|||||||||.|||||||||
  Rat   391 PHPRFTSSLLPTLEPSPNMEQPA--ELPRADTELSEGFSS-PSSLVSPSTPSSLGLSLSSTSGIG 452

Human   456 TSPSLRSLQSLLGPSSKFRHAQGTVLHRDSHITNLKGLNLTTPGESDGFCANKLRVAVPLLSSGG 520
            ||||.||||||||||||||||:||:|||||||||||||||||||||||||||:||||||||||||
  Rat   453 TSPSQRSLQSLLGPSSKFRHAEGTILHRDSHITNLKGLNLTTPGESDGFCANRLRVAVPLLSSGG 517

Human   521 QVAVLELRKPGRLPDTALPTLQNGAAVTDLAWDPFDPHRLAVAGEDARIRLWRVPAEGLEEVLTT 585
            |||||||:|||||||||||||||||||.||.||||||||||||||||||||||||..||:.||||
  Rat   518 QVAVLELQKPGRLPDTALPTLQNGAAVMDLVWDPFDPHRLAVAGEDARIRLWRVPPGGLKNVLTT 582

Human   586 PETVLTGHTEKICSLRFHPLAANVLASSSYDLTVRIWDLQAGADRLKLQGHQDQIFSLAWSPDGQ 650
            ||||||||||||.|||||||||:||||||||||:||||||||.::|:|||||||||||||||||:
  Rat   583 PETVLTGHTEKIYSLRFHPLAADVLASSSYDLTIRIWDLQAGTEQLRLQGHQDQIFSLAWSPDGK 647

Human   651 QLATVCKDGRVRVYRPRSGPEPLQEGPGPKGGRGARIVWVCDGRCLLVSGFDSQSERQLLLYEAE 715
            ||||||||||||||.|||.|.|||:||||:|||||||||||:|.|||||||||:|||||.||.|:
  Rat   648 QLATVCKDGRVRVYDPRSSPLPLQDGPGPEGGRGARIVWVCNGGCLLVSGFDSRSERQLQLYMAD 712

Human   716 ALAGGPLAVLGLDVAPSTLLPSYDPDTGLVLLTGKGDTRVFLYELLPESPFFLECNSFTSPDPHK 780
            |||.||.|:|||||||||||||||||||||||||||||||||||::||:||||||||||||||||
  Rat   713 ALAEGPSALLGLDVAPSTLLPSYDPDTGLVLLTGKGDTRVFLYEVIPEAPFFLECNSFTSPDPHK 777

Human   781 GLVLLPKTECDVREVELMRCLRLRQSSLEPVAFRLPRVRKEFFQDDVFPDTAVIWEPVLSAEAWL 845
            |.:||||||||:::||..|||||||:|||||||||||||||||||||||||||.|...|.|:||.
  Rat   778 GFILLPKTECDIQDVEFARCLRLRQTSLEPVAFRLPRVRKEFFQDDVFPDTAVTWASALDAKAWF 842

Human   846 QGANGQPWLLSLQPPDMSPVSQAPREAPARRAPSSAQYLEEKSDQQKKEELLNAMVAKLGNREDP 910
            :||||||.|||||||.|:||||||||.||||.|||||||||||||||||||||||||||||||||
  Rat   843 KGANGQPRLLSLQPPGMTPVSQAPREVPARRTPSSAQYLEEKSDQQKKEELLNAMVAKLGNREDP 907

Human   911 LPQDSFEGVDEDEWD 925
            |||||||||||||||
  Rat   908 LPQDSFEGVDEDEWD 922

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CORO7	NP_078811.3	WD40	6..428	CDD:475233	337/421 (80%)
		WD 1	75..115		33/39 (85%)
		WD40 repeat	81..124	CDD:293791	35/42 (83%)
		WD 2	124..163		30/38 (79%)
		WD40 repeat	129..165	CDD:293791	28/35 (80%)
		WD 3	166..205		32/38 (84%)
		WD40 repeat	172..208	CDD:293791	30/35 (86%)
		WD 4	209..253		35/43 (81%)
		WD40 repeat	215..256	CDD:293791	33/40 (83%)
		WD40 repeat	263..302	CDD:293791	34/38 (89%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	419..461		33/41 (80%)
		WD40	471..880	CDD:475233	352/408 (86%)
		WD40 repeat	504..540	CDD:293791	33/35 (94%)
		WD 5	542..582		34/39 (87%)
		WD40 repeat	547..591	CDD:293791	37/43 (86%)
		WD 6	592..632		33/39 (85%)
		WD40 repeat	598..634	CDD:293791	28/35 (80%)
		WD 7	635..674		34/38 (89%)
		WD40 repeat	640..677	CDD:293791	31/36 (86%)
		WD 8	728..768		36/39 (92%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	858..925		62/66 (94%)
Coro7	NP_001178568.1	WD40	7..426	CDD:475233	337/420 (80%)
		WD 1	75..115		33/39 (85%)
		WD40 repeat	81..124	CDD:293791	35/42 (83%)
		WD 2	124..163		30/38 (79%)
		WD40 repeat	129..165	CDD:293791	28/35 (80%)
		WD 3	166..205		32/38 (84%)
		WD40 repeat	172..208	CDD:293791	30/35 (86%)
		WD 4	209..253		35/43 (81%)
		WD40 repeat	215..256	CDD:293791	33/40 (83%)
		WD40 repeat	264..302	CDD:293791	34/37 (92%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	386..462		56/78 (72%)
		WD40	468..870	CDD:475233	347/401 (87%)
		WD 5	539..579		34/39 (87%)
		WD40 repeat	542..588	CDD:293791	39/45 (87%)
		WD 6	589..629		33/39 (85%)
		WD40 repeat	595..631	CDD:293791	28/35 (80%)
		WD 7	632..671		34/38 (89%)
		WD40 repeat	637..674	CDD:293791	31/36 (86%)
		WD 8	725..765		36/39 (92%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	854..922		63/67 (94%)