Protein Alignment CORO7 and coro7

DIOPT Version :10

• Sequence 1: NP_078811.3
• Gene: CORO7 / 79585
• HGNCID: 26161
• Length: 925
• Species: Homo sapiens
• Sequence 2: XP_002932508.2
• Gene: coro7 / 100492934
• XenbaseID: XB-GENE-949602
• Length: 907
• Species: Xenopus tropicalis
• Alignment Length: 926
• Identity: 527/926 - (56%)
• Similarity: 675/926 - (72%)
• Gaps: 20/926 - (2%)

Human     1 MNRFRVSKFRHTEARPPRRESWISDIRAGTAPSCRNHIKSSCSLIAFNSDRPGVLGIVPLQGQGE 65
            ||||:.|||::...:.|::|.||:||.:.::.|..|:||....:||||:|..|||||.||:.:..
 Frog     1 MNRFKTSKFKNCIPKIPKKEDWINDIGSASSSSTGNNIKCGQRVIAFNTDSAGVLGITPLEVRSG 65

Human    66 DKRRVAHLGCHSDLVTDLDFSPFDDFLLATGSADRTVKLWRLPGPGQALPSAPGVVLGPEDLPVE 130
            :||.|:.:.||:|||||..||||.|.||.|||:|:|:||||:...|.| .|..|.:.|.|. .|.
 Frog    66 EKRTVSRISCHTDLVTDFAFSPFADDLLVTGSSDQTIKLWRVSETGDA-GSLSGTLAGVEG-QVR 128

Human   131 VLQFHPTSDGILVSAAGTTVKVWDAAKQQPLTELAAHGDLVQSAVWSRDGALVGTACKDKQLRIF 195
            .|||||::|.:||:||..||::||.:::..||.|.||||.|||..||:||.|:||:||||:||||
 Frog   129 SLQFHPSADSLLVTAAAKTVQLWDLSRESKLTALEAHGDQVQSVCWSQDGVLLGTSCKDKRLRIF 193

Human   196 DPRTKPRASQSTQAHENSRDSRLAWMGTWEHLVSTGFNQMREREVKLWDTRFFSSALASLTLDTS 260
            |.|:...|.|:.|.|::::|||:.|..:..||:::||||:||||:.|||.|.||..|.|.|||.|
 Frog   194 DARSGTGAIQNAQGHDSNKDSRVQWTNSNSHLLTSGFNQVRERELLLWDIRSFSRPLTSFTLDAS 258

Human   261 LGCLVPLLDPDSGLLVLAGKGERQLYCYEVVPQQPALSPVTQCVLESVLRGAALVPRQALAVMSC 325
            .|.|:||.|.|:|||:|..:||..|||.||..:..:|:.::|||.|...||.||||:..|.||:|
 Frog   259 SGLLIPLYDYDTGLLILGAQGEGSLYCMEVSTEPHSLTQISQCVTEEQSRGLALVPKLCLDVMNC 323

Human   326 EVLRVLQLSDTAIVPIGYHVPRKAV-EFHEDLFPDTAGCVPATDPHSWWAGDNQQVQKVSLNPAC 389
            |:||:|||:|..|:||.|:|.||:| |...||||:||||.||.....||.|||:|||||||:|:.
 Frog   324 ELLRLLQLTDKFIIPISYNVQRKSVKELQVDLFPNTAGCTPALTAQDWWKGDNKQVQKVSLDPSR 388

Human   390 RPHPSFTSCLVPPAEPLPDTAQPAVMETPVGDADASEGFSSPPSSLTSPSTPSSLGPSLSSTSGI 454
            ||.|   ||.....:...:..:..::.:....:|.|. .|||.|||||||            |||
 Frog   389 RPAP---SCQGNSGKKKNEPQENDIVSSIAEPSDGST-LSSPSSSLTSPS------------SGI 437

Human   455 GTSPSLRSLQSLLGPSSKFRHAQGTVLHRDSHITNLKGLNLTTPGESDGFCANKLRVAVPLLSSG 519
            .:|.|.|||||.|||||:.||.||||||||.|||||:|::.:|||||||||.|..|.||||.:.|
 Frog   438 VSSTSQRSLQSFLGPSSRLRHTQGTVLHRDHHITNLRGISQSTPGESDGFCVNYQRAAVPLAAPG 502

Human   520 GQVAVLELRKPGRLPDTALPTLQNGAAVTDLAWDPFDPHRLAVAGEDARIRLWRVPAEGLEEVLT 584
            |||||||..:.|||||| |||:||...||||.||||:||||...|||.|||:|::|.:||::.||
 Frog   503 GQVAVLEFSQTGRLPDT-LPTVQNSVPVTDLTWDPFNPHRLVTGGEDGRIRVWQIPQKGLKKTLT 566

Human   585 TPETVLTGHTEKICSLRFHPLAANVLASSSYDLTVRIWDLQAGADRLKLQGHQDQIFSLAWSPDG 649
            .|..|||||.|:|.::||||.|:::|||||||.|||||:||.|.|...|:||:||||||||||||
 Frog   567 EPHIVLTGHNERIYTVRFHPCASDILASSSYDFTVRIWNLQTGKDVHVLRGHEDQIFSLAWSPDG 631

Human   650 QQLATVCKDGRVRVYRPRSGPEPLQEGPGPKGGRGARIVWVCDGRCLLVSGFDSQSERQLLLYEA 714
            :.|||..||.|:|:|.||....|:||||||:|.||||:||||||:.||.|||:|:|:||:.|...
 Frog   632 KYLATCSKDQRIRIYEPRKSNLPMQEGPGPEGSRGARVVWVCDGKYLLASGFNSRSDRQISLLSP 696

Human   715 EALAGGPLAVLGLDVAPSTLLPSYDPDTGLVLLTGKGDTRVFLYELLPESPFFLECNSFTSPDPH 779
            |.|:.||::...|||:||||:|.|||||.|:|||||||||.||:|:|.|.|:|||||:|:|.|.|
 Frog   697 EDLSCGPVSKTNLDVSPSTLIPHYDPDTSLLLLTGKGDTRAFLFEVLAEPPYFLECNTFSSTDSH 761

Human   780 KGLVLLPKTECDVREVELMRCLRLRQSSLEPVAFRLPRVRKEFFQDDVFPDTAVIWEPVLSAEAW 844
            ||..:|.|.:|.|.:.|::|.:||..||||||:||:|||:|||||||:||.:.:.|||.|||..|
 Frog   762 KGFQVLRKLDCAVCDAEIVRAVRLGSSSLEPVSFRVPRVKKEFFQDDLFPPSRITWEPALSAGDW 826

Human   845 LQGANGQPWLLSLQPPDMSPVSQAPREAPARRAPSSAQYLEEKSDQQKKEELLNAMVAKLGNRED 909
            |.|.:.|...::|.|..|.||||||:|||||:...|:.||:||:|:|||||||||||||||||:|
 Frog   827 LDGKDLQQRTINLCPDGMVPVSQAPKEAPARKILPSSVYLQEKTDEQKKEELLNAMVAKLGNRDD 891

Human   910 PLPQDSFEGVDEDEWD 925
            |||||:||||||||||
 Frog   892 PLPQDAFEGVDEDEWD 907

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CORO7	NP_078811.3	WD40	6..428	CDD:475233	207/422 (49%)
		WD 1	75..115		25/39 (64%)
		WD40 repeat	81..124	CDD:293791	22/42 (52%)
		WD 2	124..163		17/38 (45%)
		WD40 repeat	129..165	CDD:293791	17/35 (49%)
		WD 3	166..205		25/38 (66%)
		WD40 repeat	172..208	CDD:293791	21/35 (60%)
		WD 4	209..253		21/43 (49%)
		WD40 repeat	215..256	CDD:293791	22/40 (55%)
		WD40 repeat	263..302	CDD:293791	17/38 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	419..461		17/41 (41%)
		WD40	471..880	CDD:475233	253/408 (62%)
		WD40 repeat	504..540	CDD:293791	23/35 (66%)
		WD 5	542..582		24/39 (62%)
		WD40 repeat	547..591	CDD:293791	26/43 (60%)
		WD 6	592..632		25/39 (64%)
		WD40 repeat	598..634	CDD:293791	21/35 (60%)
		WD 7	635..674		25/38 (66%)
		WD40 repeat	640..677	CDD:293791	23/36 (64%)
		WD 8	728..768		28/39 (72%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	858..925		50/66 (76%)
coro7	XP_002932508.2	DUF1899	3..61	CDD:462645	26/57 (46%)
		WD40	80..419	CDD:475233	173/343 (50%)
		WD40 repeat	81..122	CDD:293791	22/41 (54%)
		WD40 repeat	127..163	CDD:293791	17/35 (49%)
		WD40 repeat	170..206	CDD:293791	21/35 (60%)
		WD40 repeat	213..254	CDD:293791	22/40 (55%)
		WD40 repeat	261..300	CDD:293791	17/38 (45%)
		WD40	454..871	CDD:475233	258/417 (62%)
		WD40 repeat	530..574	CDD:293791	26/43 (60%)
		WD40 repeat	579..616	CDD:293791	22/36 (61%)
		WD40 repeat	623..659	CDD:293791	22/35 (63%)
		WD40 repeat	666..710	CDD:293791	23/43 (53%)
		WD40 repeat	719..756	CDD:293791	26/36 (72%)