DRSC/TRiP Functional Genomics Resources

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Protein Alignment SPAG16 and CG3909

DIOPT Version :9

Sequence 1:NP_078808.3 Gene:SPAG16 / 79582 HGNCID:23225 Length:631 Species:Homo sapiens
Sequence 2:NP_649969.1 Gene:CG3909 / 41226 FlyBaseID:FBgn0027524 Length:331 Species:Drosophila melanogaster


Alignment Length:230 Identity:66/230 - (28%)
Similarity:110/230 - (47%) Gaps:7/230 - (3%)


- Green bases have known domain annotations that are detailed below.


Human   407 DKLATSSGDTTVKLWDLCKGDCIL---TFEGHSRAVWSCTWHSCGNFVASSSLDKTSKIWDVNS- 467
            |.|.|...|..||:|||.:.:.:.   ..:||:..|.|....|.|..:||||||.|..:||..| 
  Fly    53 DFLVTGGLDDLVKVWDLQEDNTLKLRHKLKGHALGVVSVAVSSDGQTIASSSLDSTMCLWDARSG 117

Human   468 ERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTGICEQSLYGHMHSINDAI-FDPR 531
            ::.....:|..| :.:::|.|.:..:::...|..:|::...||..||:|.........:| :.|.
  Fly   118 DKKHLLSFGPVD-LWTVQFSPCNKYVISGLNDGKISMYSVETGKAEQTLDAQNGKYTLSIAYSPD 181

Human   532 GHMIASCDACGVTKLWDFRKLLPIVSIDIGPSPGNEVNFDSSGRVLAQASGNGVIHLLDL-KSGE 595
            |..|||....|:..::|......:.:::....|...:.|..:.::|..||.:|.:.|.|: .|..
  Fly   182 GKYIASGAIDGIITIFDVAAGKVVQTLEGHAMPVRSLCFSPNSQLLLTASDDGHMKLYDVTHSDV 246

Human   596 IHKLMGHENEAHTVVFSHDGEILFSGGSDGTVRTW 630
            :..|.||.:....|.||.||:...|..||.:|:.|
  Fly   247 VGTLSGHASWVLCVAFSEDGKHFASSSSDNSVKIW 281

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SPAG16NP_078808.3 Prefoldin 160..271 CDD:298833
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 266..332
WD40 <341..631 CDD:225201 66/230 (29%)
WD40 344..631 CDD:238121 66/230 (29%)
WD 1 350..389
WD40 repeat 355..392 CDD:293791
WD 2 392..431 9/26 (35%)
WD40 repeat 398..434 CDD:293791 9/29 (31%)
WD 3 434..473 16/39 (41%)
WD40 repeat 439..475 CDD:293791 14/36 (39%)
WD 4 476..515 9/38 (24%)
WD40 repeat 482..516 CDD:293791 8/33 (24%)
WD 5 518..557 8/39 (21%)
WD40 repeat 523..559 CDD:293791 8/36 (22%)
WD 6 560..600 9/40 (23%)
WD40 repeat 565..600 CDD:293791 8/35 (23%)
WD 7 601..630 11/28 (39%)
WD40 repeat 607..630 CDD:293791 9/22 (41%)
CG3909NP_649969.1 WD40 52..323 CDD:238121 66/230 (29%)
WD40 <54..326 CDD:225201 65/229 (28%)
WD40 repeat 89..127 CDD:293791 13/37 (35%)
WD40 repeat 130..166 CDD:293791 8/35 (23%)
WD40 repeat 174..209 CDD:293791 8/34 (24%)
WD40 repeat 215..251 CDD:293791 8/35 (23%)
WD40 repeat 257..293 CDD:293791 10/25 (40%)
WD40 repeat 299..323 CDD:293791
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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