Protein Alignment BIRC7 and Diap2

DIOPT Version :10

• Sequence 1: XP_054179986.1
• Gene: BIRC7 / 79444
• HGNCID: 13702
• Length: 351
• Species: Homo sapiens
• Sequence 2: NP_477127.1
• Gene: Diap2 / 36748
• FlyBaseID: FBgn0015247
• Length: 498
• Species: Drosophila melanogaster
• Alignment Length: 320
• Identity: 89/320 - (27%)
• Similarity: 124/320 - (38%)
• Gaps: 89/320 - (27%)

Human     5 DSAKCLHRGPQPSHWAAGDGPTQE------RCGPRSLGSPVLGLDTCRAWDHVDGQILGQLRPLT 63
            |..||:......:.|...|...:|      :| ||....|::...|.:..|.     || ::|.|
  Fly   145 DHVKCVWCNGVIAKWEKNDNAFEEHKRFFPQC-PRVQMGPLIEFATGKNLDE-----LG-IQPTT 202

Human    64 EEEEEEGAGATLSRGPAFPGMGSEELRLASFYDWPLTAEVPPELLAAAGFFHTGHQDKVRCFFCY 128
            .              |..|.....:.||.:|.|||::...|...||.||.::....|:||||.|.
  Fly   203 L--------------PLRPKYACVDARLRTFTDWPISNIQPASALAQAGLYYQKIGDQVRCFHCN 253

Human   129 GGLQSWKRGDDPWTEHAKWFPSCQFLLRSKGRDFVHSVQETHSQLLGSWDPWEEPEDAAPVAPSV 193
            .||:||::.|:||.|||||.|.|||:|.:||..:|..|..|                .|..|.|.
  Fly   254 IGLRSWQKEDEPWFEHAKWSPKCQFVLLAKGPAYVSEVLAT----------------TAANASSQ 302

Human   194 PASGYPELPTPRREVQSESAQEPGAGPGPPGEPGMWRRSCGGCRRRGRAR------CAWTA---- 248
            ||:.  ..||.:.:|..:.|         |.:..:.....||..|....|      ||::.
  Fly   303 PATA--PAPTLQADVLMDEA---------PAKEALALGIDGGVVRNAIQRKLLSSGCAFSTLDEL 356

Human   249 -------------------PCPSS----LCRAATWSVLSVP-PACSCAPSAEPPSAAACA 284
                               |.||:    .|:|.|....||| |.....| |:|.:|.|.|
  Fly   357 LHDIFDDAGAGAALEVREPPEPSAPFIEPCQATTSKAASVPIPVADSIP-AKPQAAEAVA 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
BIRC7	XP_054179986.1	BIR	88..155	CDD:237989	33/66 (50%)
Diap2	NP_477127.1	BIR	12..78	CDD:237989
		BIR	112..181	CDD:197595	9/36 (25%)
		BIR	213..281	CDD:237989	33/67 (49%)
		UBA_IAPs	320..363	CDD:270506	8/51 (16%)
		RING-HC_BIRC2_3_7	442..498	CDD:438373