DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rnf13 and Rnf13

DIOPT Version :9

Sequence 1:	NP_957338.1	Gene:	rnf13 / 793981	ZFINID:	ZDB-GENE-040426-772	Length:	377	Species:	Danio rerio
Sequence 2:	NP_001102914.1	Gene:	Rnf13 / 681578	RGDID:	1594062	Length:	380	Species:	Rattus norvegicus

Alignment Length:	381	Identity:	287/381 - (75%)
Similarity:	330/381 - (86%)	Gaps:	8/381 - (2%)

- Green bases have known domain annotations that are detailed below.

Zfish     1 MLLSLGMLMLSATQIYTIFTVQIFAFLNLLPVEADISAYSFDNKTENFDDLPARFGYRLPSEGLK 65
            ||||:|||||||||:|||.|||:|||||||||||||.||:|:|.::.|:|||||||||||:||||
  Rat     1 MLLSIGMLMLSATQVYTILTVQLFAFLNLLPVEADILAYNFENASQTFEDLPARFGYRLPAEGLK 65

Zfish    66 GFLIGARPENACVPIEPPPQRENLSSAFIVLIRRFDCNFDIKVLHAQKAGYKAAIVHNVDSDDLI 130
            ||||.::|||||.||.|||.::|.|..|||||||.|||||||||:||:|||||||||||||||||
  Rat    66 GFLINSKPENACEPIVPPPLKDNSSGTFIVLIRRLDCNFDIKVLNAQRAGYKAAIVHNVDSDDLI 130

Zfish   131 SMGSEDLDILKQIDIPSVFIGEEAANSLKEDYIYEKGGHVILMPDFSLPLEYYLIPFLIIVGICL 195
            ||||.|:||||:||||||||||.:|||||:::.|||||||||:|:.|||||||||||||||||||
  Rat   131 SMGSNDIDILKKIDIPSVFIGESSANSLKDEFTYEKGGHVILVPELSLPLEYYLIPFLIIVGICL 195

Zfish   196 ILIVVFMITKFVQDRHRARRSRLRKDQLKKLPIHKFKKGDSYDVCAICLDEYEEGERLRVLPCSH 260
            ||||:||||||||||||.||:|||||||||||:|||||||.||||||||:|||:|::||:|||||
  Rat   196 ILIVIFMITKFVQDRHRNRRNRLRKDQLKKLPVHKFKKGDEYDVCAICLEEYEDGDKLRILPCSH 260

Zfish   261 AYHCKCVDPWLTKTKKTCPVCKQKVVPSDGDSESDSDSVDSGGEDNEVSENTPLLRSLASTSAHS 325
            ||||||||||||||||||||||||||||.|||:||:   ||..|:|:|||:||||...||....|
  Rat   261 AYHCKCVDPWLTKTKKTCPVCKQKVVPSQGDSDSDT---DSSQEENQVSEHTPLLPPSASARTQS 322

Zfish   326 FGSMSASLSQHDAGSSDYD----ERSDSSDSEEEVTVETVVVQLQ-QGRPDDTEAN 376
            |||:|.|.|.|...||||:    |.:||||::.|:|..:|||||| .|.||...||
  Rat   323 FGSLSESHSHHMTESSDYEDDDNEETDSSDADNEITDHSVVVQLQPNGEPDYNIAN 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rnf13	NP_957338.1	PA_C_RZF_like	23..180	CDD:239038	120/156 (77%)
rnf13	NP_957338.1	zf-RING_2	238..282	CDD:290367	38/43 (88%)
Rnf13	NP_001102914.1	PA_C_RZF_like	23..180	CDD:239038	120/156 (77%)
		RING-H2_RNF167	238..283	CDD:319711	39/44 (89%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	285..380		52/97 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	148	1.000	Domainoid score	I17267
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	587	1.000	Inparanoid score	I5136
OMA	1	1.010	-	-		QHG51404
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	1	1.000	-	-		FOG0001489
OrthoInspector	1	1.000	-	-		oto71461
orthoMCL	1	0.900	-	-		OOG6_103040
Panther	1	1.100	-	-	LDO	PTHR22765
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X670
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.980