DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment snip1 and CG17168

DIOPT Version :9

Sequence 1:	NP_001020641.1	Gene:	snip1 / 793873	ZFINID:	ZDB-GENE-041026-3	Length:	374	Species:	Danio rerio
Sequence 2:	NP_001015254.1	Gene:	CG17168 / 3354996	FlyBaseID:	FBgn0039943	Length:	421	Species:	Drosophila melanogaster

Alignment Length:	417	Identity:	170/417 - (40%)
Similarity:	241/417 - (57%)	Gaps:	64/417 - (15%)

- Green bases have known domain annotations that are detailed below.

Zfish     3 NRRRHRDSPVRDVK------TKIKQERLSPARPPRARRHS-SGSSRDSSSPAQRRRDSRSPVRRK 60
            :::|:::..:...:      ||:....||..:..:.|..: |.||.|||:.:::...|.....||
  Fly     2 SKQRNKEHELEQQRTGHEGDTKMSDRNLSKTKKIKQRATADSSSSSDSSNESKKSNHSSLSPNRK 66

Zfish    61 DRSPARRDRSSGRQQERSPRPRRSRSPHRNTEARIKREQ-DDPRGSESHRH--RERRD------D 116
            .|:..:|.|.|.:.||:    |..:..|.:.:...:|.: |.|..|.|||:  |:||:      :
  Fly    67 QRTAGKRQRDSSQSQEK----RHKQLTHPSEDVHEQRSKWDSPERSNSHRNSTRQRRNTRSRSRE 127

Zfish   117 SNDRRLKREAERPRQRD-------------------------RGREQDRQRGRIRDAHIQEQQQA 156
            .::|...|:.||.::||                         :.||:|||| |..:.....:.|:
  Fly   128 RSERERDRDCERNKERDYNMQSSKERWQRSPALRHRSRSSERKNRERDRQR-RPTERRPVRRSQS 191

Zfish   157 ERER-HNER---RRENRLRQEAQSGGAEEMLEFGGENNDESAPA-----AEKEKPNFELSGALVE 212
            .|:| |..|   :|..|.::...|...|:.....|:..||..||     .:||||||.|||||.|
  Fly   192 PRDRCHGGRDLDQRRQRNQRHNNSNKNEDDHYVWGKEVDEKVPAENDVPVDKEKPNFGLSGALTE 256

Zfish   213 DTNTFRGEVIKYNEPPEARIPKRRWRLYPFKNDEPLPVMYIHRQSAYLLGRLRKIADIPIDHPSC 277
            |||...|.|:||:||||||.|||||||||||.:..||.::|||||.:|:||.||:.|:.:|||||
  Fly   257 DTNKLNGVVVKYSEPPEARKPKRRWRLYPFKGETALPTLHIHRQSCFLVGRDRKVVDLAVDHPSC 321

Zfish   278 SKQHAVFQYRLVEFTRVDGTAGRRVKPYIIDLGSGNGTYLNNQRIEPQRYYELKEKDVLKFGFSS 342
            |||||..|||||.|.|.||:.|:||:.|:|||.|.|||:|||::|:.::||||.||||:||||||
  Fly   322 SKQHAALQYRLVPFEREDGSHGKRVRLYLIDLDSANGTFLNNKKIDARKYYELIEKDVIKFGFSS 386

Zfish   343 REYVLLHEFSDTTEVDAKKKEEEEEED 369
            ||||||||.|         ||::|::|
  Fly   387 REYVLLHENS---------KEDQEDDD 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
snip1	NP_001020641.1	FHA	236..339	CDD:238017	64/102 (63%)
snip1	NP_001020641.1	FHA	<253..344	CDD:224630	59/90 (66%)
CG17168	NP_001015254.1	FHA	280..395	CDD:238017	76/114 (67%)
CG17168	NP_001015254.1	FHA	<294..411	CDD:224630	72/120 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	143	1.000	Domainoid score	I4583
eggNOG	1	0.900	-	-		E1_KOG1882
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	280	1.000	Inparanoid score	I2876
OMA	1	1.010	-	-		QHG52032
OrthoDB	1	1.010	-	-		D955935at2759
OrthoFinder	1	1.000	-	-		FOG0004489
OrthoInspector	1	1.000	-	-		oto41401
orthoMCL	1	0.900	-	-		OOG6_102703
Panther	1	1.100	-	-	LDO	PTHR23308
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2234
SonicParanoid	1	1.000	-	-		X4267
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.870