Protein Alignment OR4K5 and 5-HT7

DIOPT Version :9

• Sequence 1: NP_001005483.1
• Gene: OR4K5 / 79317
• HGNCID: 14745
• Length: 323
• Species: Homo sapiens
• Sequence 2: NP_001263131.1
• Gene: 5-HT7 / 43669
• FlyBaseID: FBgn0004573
• Length: 564
• Species: Drosophila melanogaster
• Alignment Length: 454
• Identity: 85/454 - (18%)
• Similarity: 154/454 - (33%)
• Gaps: 182/454 - (40%)

Human     4 SNSSVV--------------SEFVLLGLCSSQKLQLFYFCFFSVLYTVIVL----GNLLIILTVT 50
            ||:::|              .||||..|.|         .|.|::..:::|    ||:|:.:.|.
  Fly   133 SNTTLVPLSDTPLLLEEFAAGEFVLPPLTS---------IFVSIVLLIVILGTVVGNVLVCIAVC 188

Human    51 SDTSLHSPMYFLLGNLSFVDICQASFATPKMIADFLSAHETISFSGCIAQIF--FIHLFTGGEMV 113
            ....|..|..:||.:|:..|:|.|....|  :|......|..:|...:..|:  |..|.....::
  Fly   189 MVRKLRRPCNYLLVSLALSDLCVALLVMP--MALLYEVLEKWNFGPLLCDIWVSFDVLCCTASIL 251

Human   114 LLVSMAYDRYVAICKPLYYVVIMSRRTCTVLVMISWAVSLVHTLSQLSFTVN-------LPFCGP 171
            .|.:::.|||:||.|||.|.|..:.|...:.|.|.|..:...:|..|....|       .|.|
  Fly   252 NLCAISVDRYLAITKPLEYGVKRTPRRMMLCVGIVWLAAACISLPPLLILGNEHEDEEGQPIC-- 314

Human   172 NVVDSFFCDLPRVTKLACLDSYIIEILIVV----------------------------------- 201
            .|..:|...:     .|.|.|:.|.:.:::
  Fly   315 TVCQNFAYQI-----YATLGSFYIPLSVMLFVYYQIFRAARRIVLEEKRAQTHLQQALNGTGSPS 374

Human   202 -------------------------------------------------------NSGIL----- 206
                                                                   ::|:|
  Fly   375 APQAPPLGHTELASSGNGQRHSSVGNTSLTYSTCGGLSSGGGALAGHGSGGGVSGSTGLLGSPHH 439

Human   207 ------------SLSTFSLLVSSYIIILVTVWLKSSAAMAKAFSTLASHIAVVILFFGPCIFIYV 259
                        :.:|..:::|::.:..:..::   .|:.:.|.|:  |:
  Fly   440 KKLRFQLAKEKKASTTLGIIMSAFTVCWLPFFI---LALIRPFETM--HV--------------- 484

Human   260 WPFTISPLDKFLAIFYTVFTPVLNPIIYTLRNRDMKAAVRKIVNHYLRPRRISEMSLVVRTSFH 323
             |.::|.|  ||.:.|.  ..:||||||...|||.:...::|:  |.   |.|.::.::|.:::
  Fly   485 -PASLSSL--FLWLGYA--NSLLNPIIYATLNRDFRKPFQEIL--YF---RCSSLNTMMRENYY 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
OR4K5	NP_001005483.1	7tm_4	31..301	CDD:304433	70/389 (18%)
		7tm_1	41..287	CDD:278431	63/361 (17%)
5-HT7	NP_001263131.1	7tm_4	173..>342	CDD:304433	46/177 (26%)
		7tm_1	179..507	CDD:278431	63/361 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910