Protein Alignment OR4K5 and srsx-3

DIOPT Version :9

• Sequence 1: NP_001005483.1
• Gene: OR4K5 / 79317
• HGNCID: 14745
• Length: 323
• Species: Homo sapiens
• Sequence 2: NP_505041.1
• Gene: srsx-3 / 190823
• WormBaseID: WBGene00022408
• Length: 310
• Species: Caenorhabditis elegans
• Alignment Length: 279
• Identity: 54/279 - (19%)
• Similarity: 109/279 - (39%)
• Gaps: 52/279 - (18%)

Human     6 SSVVSEFVLLGLCSSQKLQLFYFCFFSVLYTVI-VLGNLLIILTVTSDTSLHSPMYFLLGNLSFV 69
            ||.|:  ::..:|.|.::         |::.|: :.||:..:.......:|.|..|::...||..
 Worm     2 SSTVA--MINQICISTEI---------VVFNVLGLFGNINFLCLTYIKPALRSKSYYIQCALSVS 55

Human    70 DICQASFATPKMIADF--LSAHETISFSGCIAQIFFIHLFTGGEMVLLVSMAYDRYVAICKPLYY 132
            .|....|..|..:..|  :.....|.|......||||    ..:.|:::.:..|.::.:....:|
 Worm    56 HIFCLLFELPNAVLLFTGIQLRRNICFPAISLYIFFI----CAQAVIMLMLVVDLFIIVFFTTFY 116

Human   133 VVIMSRRTCTVLVMISWAVSLVHTLSQLSFTVNLPFCGPNVVDSFFCDLPRVTKLACLDSYIIEI 197
            ..|.:.....:::.|.:..|        :|||...|...:.....||:.|            |.:
 Worm   117 RRIENTTYTAMMLFIPFVYS--------AFTVAWGFVKMDDELVIFCNPP------------ISL 161

Human   198 LIVVNS--GILSLSTFSLLVSSYIIILVTVWL---KSSAAMAKAFSTLASHIAVVILFFGPCIFI 257
            ..||:.  .:.:::..|:.:..::.:::|...   |..:...|....|  .::||       :|:
 Worm   162 HPVVSRWWSMSNVALNSITLCLFLFLIITFHFRGKKQKSDTRKLMKRL--KVSVV-------VFV 217

Human   258 YVWPFTISPLDKFLAIFYT 276
            :.|......:|.|:||..|
 Worm   218 FSWYMCTLGVDLFVAIGMT 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
OR4K5	NP_001005483.1	7tm_4	31..301	CDD:304433	49/254 (19%)
		7tm_1	41..287	CDD:278431	47/243 (19%)
srsx-3	NP_505041.1	TM helix 1	17..38	CDD:341315	4/29 (14%)
		7TM_GPCR_Srsx	21..277	CDD:255903	48/249 (19%)
		TM helix 2	45..69	CDD:341315	6/23 (26%)
		TM helix 3	81..111	CDD:341315	7/33 (21%)
		TM helix 4	124..143	CDD:341315	5/26 (19%)
		TM helix 5	170..191	CDD:341315	1/20 (5%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910