Protein Alignment DCAF10 and CG30116

DIOPT Version :10

• Sequence 1: NP_077321.3
• Gene: DCAF10 / 79269
• HGNCID: 23686
• Length: 559
• Species: Homo sapiens
• Sequence 2: NP_725799.1
• Gene: CG30116 / 37126
• FlyBaseID: FBgn0028496
• Length: 1922
• Species: Drosophila melanogaster
• Alignment Length: 494
• Identity: 105/494 - (21%)
• Similarity: 164/494 - (33%)
• Gaps: 180/494 - (36%)

Human   151 LYGSIHPADSVYLSTRTHGAV----------FNLEYSPDGSVLTVACEQTEVLL----------- 194
            |||.:   .|.:.|||.|..:          :|||      :|.|.|:|..::.
  Fly   395 LYGQV---GSWFGSTRVHRVIRFAKATPRSAYNLE------LLRVICQQISIIFNIPEGYLPKDA 450

Human   195 -FDPISSKHIKT----LSEAHEDCVNNIRFLDNRLFATCSDDTTIALWDLRKLNTKVCTLHGHTS 254
             |||:   :|.|    |....||..|::.||              .:.||..||...|.:....|
  Fly   451 SFDPL---YINTWFQNLLRRVEDMGNDVLFL--------------FIDDLHLLNPLDCDIVTALS 498

Human   255 WV-------------------------------KNIEY----------------------DTNTR 266
            |:                               |:|||                      |.:..
  Fly   499 WLPTSLPWNVQIICSSTTPVEQLKFTPMQRDRFKSIEYQFDLNMGDYATKLKIPPQCIPGDVSFA 563

Human   267 LLVTSGFD------GNVIIWDTNRYTEDGCPHKKFFHTRFLMRMRLTPDCSKMLISTSSGY---- 321
            |.|...||      |...:.|...|..  |.......|. |:.:.:..|..:.||.|.:|:
  Fly   564 LYVEQQFDQLERHYGRQAVGDLASYIT--CSEYGLSETE-LLELLMPTDDPESLIETKNGHFSFA 625

Human   322 -----------LLILHDLDLTKSLEV---GSYPILRARRTTSSSDLTTS-----SSSSGPRVSGS 367
                       ||:|||..::..:.:   .:|....|:|.......|.|     ::...|:....
  Fly   626 TFKKIHREMDLLLLLHDKIMSGKVLIQWRHNYCASVAKRRYMDVQRTRSLHCELANLFFPQDEDE 690

Human   368 PCHHSDSNSSEKHMSRASQREGVSPRNSLEVVTPEVLG---ESDHGNCITSLQLHP--------- 420
            ....::||.||. .|..|.::....::||..|:....|   .|.|.|..||...:|
  Fly   691 STLENESNRSES-KSVISLKDRDREKDSLSAVSAVSAGRKSSSTHHNDDTSTFYNPIAADVSYSM 754

Human   421 ----KGWATLLRCSSNSDD-----EECTCVYEFQEGAPVRPVS---PRCSL-RLTHYIEEANVGR 472
                :.|..|:|    |||     :...|.::|...| |:.||   .||.: .:..||.:.::
  Fly   755 RHVEESWHHLMR----SDDTTRFKQIAVCNFDFLLAA-VQTVSISYLRCLIEHVRCYILDRDI-- 812

Human   473 GYIKELCF-----SPDGRMISSPHGYGIRLLGFDKQCSE 506
                ||.:     |.| .:...|...|.:|:.:.:..||
  Fly   813 ----ELIYYTIRKSSD-VLTRDPMQLGSQLISWLRPISE 846

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DCAF10	NP_077321.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..119
		WD 1	166..205		13/60 (22%)
		WD40	<168..>334	CDD:441893	51/265 (19%)
		WD40 repeat	172..207	CDD:293791	12/50 (24%)
		WD 2	209..247		9/37 (24%)
		WD40 repeat	214..250	CDD:293791	8/35 (23%)
		WD 3	251..290		14/97 (14%)
		WD40 repeat	256..282	CDD:293791	10/84 (12%)
		WD 4	296..335		12/53 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	350..396		9/50 (18%)
		WD 5	408..448		13/57 (23%)
		WD 6	470..508		9/42 (21%)
		WD40	517..555	CDD:197651
		WD 7	526..559
CG30116	NP_725799.1	WD40	<897..1057	CDD:441893
		WD40 repeat	901..937	CDD:293791
		WD40 repeat	942..982	CDD:293791
		WD40 repeat	988..1024	CDD:293791
		WD40	991..1491	CDD:441893
		WD40 repeat	1029..1064	CDD:293791
		WD40 repeat	1071..1106	CDD:293791
		WD40 repeat	1112..1147	CDD:293791
		WD40 repeat	1216..1252	CDD:293791
		WD40 repeat	1258..1294	CDD:293791
		WD40 repeat	1299..1335	CDD:293791
		WD40 repeat	1340..1374	CDD:293791
		WD40 repeat	1379..1415	CDD:293791
		WD40 repeat	1421..1458	CDD:293791
		WD40 repeat	1464..1488	CDD:293791