Protein Alignment HSD17B8 and CG31546

DIOPT Version :9

• Sequence 1: NP_055049.1
• Gene: HSD17B8 / 7923
• HGNCID: 3554
• Length: 261
• Species: Homo sapiens
• Sequence 2: NP_730973.1
• Gene: CG31546 / 40691
• FlyBaseID: FBgn0051546
• Length: 264
• Species: Drosophila melanogaster
• Alignment Length: 253
• Identity: 72/253 - (28%)
• Similarity: 117/253 - (46%)
• Gaps: 17/253 - (6%)

Human    13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQADVS 77
            :.|:|||.||||.|.:...:..||.:|..|.:.......::.....|.:   |.|    ...|:.
  Fly    15 VVLITGAASGIGAAAAEMFSKLGACLALVDREEEGLICVMKRCMKMGHE---PYG----IAGDLL 72

Human    78 EARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQAL 142
            :.....|:..:....:.....|:|:.|||.....|.......:..|:..|::..|.:|:.....|
  Fly    73 KPPEIECIARKTTERYEGKLDVLVNGAGIMPTGTLQSTELACFTHVMEANVRSGFYLTKLLLPQL 137

Human   143 VSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMT 207
            :.  |:|||:|:||:.|.........|..|||.|...|::.|.:||..|:|.|:|.||.|.|.:
  Fly   138 LQ--CKGSIVNVSSVCGLRAFPNLVAYNMSKAAVDQFTRSLALDLGPQGVRVNAVNPGVIRTNL- 199

Human   208 QKVPQKVVDKITEMI-------PMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGG 258
            ||..........|.:       .:|.:|:|::||..:.|||||.:.::||.::.|.||
  Fly   200 QKAGGMDEQSYAEFLEHSKKTHALGRIGEPKEVAAAICFLASELASFVTGVTLPVDGG 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HSD17B8	NP_055049.1	BKR_SDR_c	13..260	CDD:187594	72/253 (28%)
CG31546	NP_730973.1	fabG	9..257	CDD:235975	70/251 (28%)
		NADB_Rossmann	11..261	CDD:304358	72/253 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000019
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910