Protein Alignment HSD17B8 and CG12171

DIOPT Version :9

• Sequence 1: NP_055049.1
• Gene: HSD17B8 / 7923
• HGNCID: 3554
• Length: 261
• Species: Homo sapiens
• Sequence 2: NP_649563.1
• Gene: CG12171 / 40690
• FlyBaseID: FBgn0037354
• Length: 257
• Species: Drosophila melanogaster
• Alignment Length: 259
• Identity: 80/259 - (30%)
• Similarity: 128/259 - (49%)
• Gaps: 23/259 - (8%)

Human    10 RSALALVTGAGSGIGRAVSVRLAGEGA--TVAACDLDR--AAAQETVRLLGGPGSKEGPPRGNHA 70
            :..:.:||||.||||...||.||..|.  |:...:||:  ..|::.|...|.|..:......:.:
  Fly     5 KDKVIIVTGASSGIGAGTSVLLAKLGGLLTIVGRNLDKLNETAEQIVAAGGAPALQVAADINSES 69

Human    71 AFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVT 135
            ..|..||...|....::           |:|:.|||.:...:.:.|.:.:|:|:..|::..:.:|
  Fly    70 DVQGIVSATLAKHGRID-----------VLVNNAGILELGSIENTSLEQFDRVMNTNVRSLYQLT 123

Human   136 QAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPG 200
            ......|:..  :|:|:|:||:.|.....|...|..|||.|...|:..|.||...|:|.|||.||
  Fly   124 HLVTPELIKT--KGNIVNVSSVNGIRSFPGVLAYNVSKAAVDQFTRCVALELAPKGVRVNSVNPG 186

Human   201 FIATPMTQK--VPQKVVDKITEMIPMGH-LGDP---EDVADVVAFLASEDSGYITGTSVEVTGG 258
            .|.|.:.::  :.|:...|..|...:.| ||.|   ::||..:|||||:::.:.||.|:.|.||
  Fly   187 VIITELQRRGGLDQEAYVKFLEHAKVTHALGRPGEVKEVAAAIAFLASDEASFSTGISLPVDGG 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HSD17B8	NP_055049.1	BKR_SDR_c	13..260	CDD:187594	80/256 (31%)
CG12171	NP_649563.1	fabG	2..251	CDD:235975	80/259 (31%)
		NADB_Rossmann	4..254	CDD:304358	80/259 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000019
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1710
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.940