DRSC/TRiP Functional Genomics Resources

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Protein Alignment SLC39A7 and Zip99C

DIOPT Version :10

Sequence 1:NP_008910.2 Gene:SLC39A7 / 7922 HGNCID:4927 Length:469 Species:Homo sapiens
Sequence 2:NP_733319.1 Gene:Zip99C / 43533 FlyBaseID:FBgn0039714 Length:355 Species:Drosophila melanogaster


Alignment Length:372 Identity:135/372 - (36%)
Similarity:186/372 - (50%) Gaps:89/372 - (23%)


- Green bases have known domain annotations that are detailed below.


Human   133 TLWAYALGATVLISAAPFFVLFLIPVES-------NSPRHRSLLQILLSFASGGLLGDAFLHLIP 190
            |.|.::|..:|:|..:..|.|.:||.|.       ..|....||::|||||.||||||.||||:|
  Fly    34 TPWVFSLLGSVVIGLSGIFPLIIIPTEEKMAKEGYKDPADSKLLRVLLSFAVGGLLGDVFLHLLP 98

Human   191 HALE-----PHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHSHGH 250
            .|.|     |.||                |.|..||||||||:.|.:|||..            .
  Fly    99 EAWEGDNQDPSSH----------------PSLRSGLWVLSGILIFTIVEKIF------------S 135

Human   251 GHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQ-----KRRGGSTVPKD------------ 298
            |:|                     |::||..:.:.|:     .||.|..:|:.            
  Fly   136 GYA---------------------SADEENPQPKCVEIANCLLRRHGGQLPEGETSESCGGACDI 179

Human   299 ---GPV----RPQNAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVL 356
               |.|    ..:...:|::....:|:|||||.|:...|||.|||:..||......|||.|..:|
  Fly   180 EDVGKVCFLREQEQKSKERKEQPKKVAGYLNLLANSIDNFTHGLAVAGSFLVSFRHGILATFAIL 244

Human   357 LHEVPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWVLP 421
            |||:||||||||||::||.|:..|.|.|||||...|.|   ||:..||: |...|..|...|::|
  Fly   245 LHEIPHEVGDFAILLRSGFSRWDAARAQLLTAGAGLLG---ALVAIGGS-GVTSAMEARTSWIMP 305

Human   422 FTAGGFIYVATVSVLPELLREASPLQSLLEVLGLLGGVIMMVLIAHL 468
            ||||||:::|.|:|||:||:|....:|:.::|.|:.|:.:|.::..|
  Fly   306 FTAGGFLHIALVTVLPDLLKEEERKESIKQLLALVFGIALMAVMTML 352

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SLC39A7NP_008910.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 42..121
Zip 132..446 CDD:396884 129/348 (37%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 242..310 12/91 (13%)
Zip99CNP_733319.1 Zip 34..350 CDD:396884 134/368 (36%)
Blue background indicates that the domain is not in the aligned region.

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