Protein Alignment SLC39A7 and Zip71B

DIOPT Version :9

• Sequence 1: NP_001070984.1
• Gene: SLC39A7 / 7922
• HGNCID: 4927
• Length: 469
• Species: Homo sapiens
• Sequence 2: NP_001097608.1
• Gene: Zip71B / 39626
• FlyBaseID: FBgn0036461
• Length: 572
• Species: Drosophila melanogaster
• Alignment Length: 490
• Identity: 133/490 - (27%)
• Similarity: 209/490 - (42%)
• Gaps: 129/490 - (26%)

Human    58 HSHAHGHGHTHESIWHGHTHDHDHGH----------------------SHEDLHHGHSHGYSHES 100
            ||::.......|.:   ..||..|.|                      :|.|||    ...::..
  Fly   115 HSNSQSEAEVPEFL---EIHDPKHRHPRESSEPVAACLSPKSLLSLIVNHNDLH----KNIAYRK 172

Human   101 LYHRGH------GHDHEHSHGGYGESG----------APGIKQDLD----------AVTL----- 134
            |..:..      .|:.|..:..:..|.          .|.:...:|          :|.|
  Fly   173 LLIKNDVSSTDGVHNSEEEYNEFINSVRITPRAFMKLCPALLAQIDNGVCKQPAVRSVNLNDKNQ 237

Human   135 -----WAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHALE 194
                 |.||....:::||.....:.|:|: ..|..::.:|:.|:|.|.|.|.|||.:||:||||.
  Fly   238 KIWYAWIYASITMLILSACGLLGILLVPL-MKSAAYQEILKFLVSIAVGTLAGDALMHLLPHALF 301

Human   195 PHSHHTLEQPG-----HGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHVKG---GHGHSHGHG 251
            ....|..|..|     ..|.||.:..:| .|...|:.:..:: :|..:..:||   |||||||||
  Fly   302 KEEKHEEEVTGINPLESDHKHSNEAALL-CGCTFLAALFMYM-LENLIPLLKGGKPGHGHSHGHG 364

Human   252 HAHSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRRGGSTVPKDGPVRPQNAEEEKRGLD-- 314
            |:|..   ||||       .||.::::             ...:|   |.|..|...::..||
  Fly   365 HSHGR---SHGH-------MEKPAAKD-------------AIDLP---PPRELNVMLQEAKLDEK 403

Human   315 -----LRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVGDFAILVQSG 374
                 |....::.:..|..||.||||||||:|......|..|...||.||:|||:||||:|:|:|
  Fly   404 TPDRPLTPVAFMVIIGDGLHNLTDGLAIGAAFASDPVTGFATAFAVLCHELPHELGDFALLLQTG 468

Human   375 CSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPG---WVLPFTAGGFIYVATVSVL 436
            .|.::|:.:.::::|.:..|.         :||..|| |.|.|   |:...|||.|:|:|...::
  Fly   469 VSMRRAVYMNIVSSVLSFVGM---------SVGLFIA-GIGDGMTQWIYAATAGSFLYIAFADLV 523

Human   437 PELL------REASPLQSLLEVLG-LLGGVIMMVL 464
            |.:.      :...|...::::.| ||||:||:.:
  Fly   524 PTMSVAHNPEKAKDPKGIIIQIFGILLGGLIMLAI 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC39A7	NP_001070984.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..121		14/90 (16%)
		Zip	132..446	CDD:308248	108/347 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	242..310		22/70 (31%)
Zip71B	NP_001097608.1	Zip	242..559	CDD:280666	114/356 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0428
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D657777at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820