Protein Alignment SLC39A7 and foi

DIOPT Version :10

• Sequence 1: NP_008910.2
• Gene: SLC39A7 / 7922
• HGNCID: 4927
• Length: 469
• Species: Homo sapiens
• Sequence 2: NP_523974.3
• Gene: foi / 38976
• FlyBaseID: FBgn0024236
• Length: 706
• Species: Drosophila melanogaster
• Alignment Length: 587
• Identity: 137/587 - (23%)
• Similarity: 193/587 - (32%)
• Gaps: 238/587 - (40%)

Human    71 IWHGHTHDHDHGHSHEDLHH-------------------------GHSHGYSHESLYHRGHGHDH 110
            :.|...|||.|.|.||:..|                         .::|....|:........|.
  Fly   151 VHHVQPHDHHHAHHHEEEDHSLQLNNCTLIQNGTTSNVICPSLPNNNTHPLGKEAKNFTLSDKDL 215

Human   111 EH-----------SHGGYGESGAPGIKQDLDAVT-------------LWAYAL------GATVLI 145
            .|           ..||..|   |.|..|:|...             :|.||.      |...|:
  Fly   216 LHLCPILLYELKAQSGGCIE---PAILSDIDTTEELLEAEKDKDIFYVWIYAFISVFACGILGLV 277

Human   146 SAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHALEPHSHHTLEQPGHGHSH 210
            ..|      :||. ..|..::.::|.|::.|.|.:.|||.|||:||:|.            |...
  Fly   278 GVA------IIPF-MGSRYYKYIIQYLVALAVGTMTGDALLHLLPHSLA------------GQDE 323

Human   211 SGQGPILSVGLWVLSGIVAFLVVE----------------------------------------- 234
            .|   ::..||..|.||:.|.|:|
  Fly   324 RG---MIMKGLGCLGGIIFFYVMEHALTMISEWRKSVEKKETKKPSRAKVMRDPDSSVNNSVAGD 385

Human   235 -----KF------------------------------------VRHVKGGHGHSHG--------- 249
                 |:                                    |..::.|.|...|
  Fly   386 KICKQKYSSYPYCYDEITMNNKQSEWMHLPFDVAAGAGGDAPSVAELRNGVGDHDGSNDMAAAAE 450

Human   250 ---------------HGHAHSHTRGSHGHGRQERST----------------KEKQSS------- 276
                           |.|.|.|......|..|:.:|                |:|.|.
  Fly   451 SLISPLHTNCVEMNHHNHNHKHNSHQQNHEGQDSNTIVTDLDGNAVYAVNKAKDKDSRNDHVTVI 515

Human   277 -EEEEKETRGVQKRRGGSTVPKDGPVRPQNAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGAS 340
             .|.|....|...|.|....|.:               .|....::.:..|..||||||:||||:
  Fly   516 LREHESSHHGHSHRHGHVHSPPE---------------TLSAVAWMIIMGDGLHNFTDGMAIGAA 565

Human   341 FRGGRGLGILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGA 405
            |......|..|::.|..||:|||:||||||:::|.|.|.|:...|||.|.:..|     :..|.|
  Fly   566 FAENIAGGFSTSLAVFCHELPHELGDFAILIKAGMSVKSAVYYNLLTGVLSFIG-----MIFGIA 625

Human   406 VG--SEIAGGAGPGWVLPFTAGGFIYVATVSVLPELLREASPL-QSLLEVLGLLGGVIMMVLIAH 467
            .|  .::|     .|:....||.|||:|.|.::||:......| |.||::||:|.||.:|:|||.
  Fly   626 FGQSQDVA-----QWMFAVAAGLFIYIALVDMMPEISASHKSLGQFLLQILGMLSGVGIMLLIAL 685

Human   468 LE 469
            .|
  Fly   686 YE 687

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC39A7	NP_008910.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..121		16/85 (19%)
		Zip	132..446	CDD:396884	103/464 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	242..310		19/115 (17%)
foi	NP_523974.3	Zip	258..684	CDD:396884	114/472 (24%)