Protein Alignment SLC39A7 and Zip48C

DIOPT Version :10

• Sequence 1: NP_008910.2
• Gene: SLC39A7 / 7922
• HGNCID: 4927
• Length: 469
• Species: Homo sapiens
• Sequence 2: NP_610712.1
• Gene: Zip48C / 36273
• FlyBaseID: FBgn0033665
• Length: 341
• Species: Drosophila melanogaster
• Alignment Length: 407
• Identity: 82/407 - (20%)
• Similarity: 138/407 - (33%)
• Gaps: 131/407 - (32%)

Human   116 GYGESGAPGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGL 180
            |||    |..:..|..:..|.       |.:|....|:|   |..|   .|..|...|.||:|.:
  Fly     4 GYG----PVTQALLGTLLTWG-------LTAAGAALVIF---VRGN---QRRSLDAALGFAAGVM 51

Human   181 LGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVV------------ 233
            :..:|..|:..|:|      :.:..|                 |.|:.|||.|
  Fly    52 IAASFWSLLKPAIE------MAESSH-----------------LYGVYAFLPVAGGFLLGSIFVY 93

Human   234 --EKFVRHVKGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSE--EEEKETRGV-------- 286
              :|.:.::                  |.:......:.|:.|..::  .|:.:..||
  Fly    94 GCDKLMSYL------------------GLNSTNMMIQMTQSKAKADIAIEDSKRNGVAPDRLASK 140

Human   287 -----------------QKRRGGSTVPKDGPVRPQNAEEEKRGLDL-----RVSGYLNLAADLAH 329
                             ::|:.|:::.:.........||::|..|.     |:  .|.:.|...|
  Fly   141 SLDSFSDCLSVQHSGESRRRKKGASINEMEQCTYTTPEEQQRAEDALSQWKRI--MLLVVAITVH 203

Human   330 NFTDGLAIGAS-----------FRGGRGLGILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRL 383
            |..:|||:|.|           |...|.|.|    .:.:...|..:.....|..:|.|.|:|:
  Fly   204 NIPEGLAVGVSFGAIGSTNSSTFESARNLAI----GIGIQNFPEGLAVSLPLHAAGFSVKRAL-- 262

Human   384 QLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWVLPFTAGGFIYVATVSVLPELLREASPLQS 448
                ..|.|:|....:....|||....|....| :.|.|.||..||:.:..:|||.....:   .
  Fly   263 ----WYGQLSGMVEPIFGVLGAVAVTFANLILP-YALSFAAGAMIYIVSDDILPEAHASGN---G 319

Human   449 LLEVLGLLGGVIMMVLI 465
            .:...|.:.|.::|:.:
  Fly   320 TIATWGTVSGFLIMMCL 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC39A7	NP_008910.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..121		3/4 (75%)
		Zip	132..446	CDD:396884	74/370 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	242..310		10/94 (11%)
Zip48C	NP_610712.1	ZupT	23..339	CDD:440197	75/377 (20%)