Protein Alignment TMEM43 and tmem43

DIOPT Version :10

• Sequence 1: NP_001394203.1
• Gene: TMEM43 / 79188
• HGNCID: 28472
• Length: 401
• Species: Homo sapiens
• Sequence 2: NP_001427784.1
• Gene: tmem43 / 406520
• ZFINID: ZDB-GENE-040426-2348
• Length: 391
• Species: Danio rerio
• Alignment Length: 381
• Identity: 202/381 - (53%)
• Similarity: 272/381 - (71%)
• Gaps: 7/381 - (1%)

Human    23 PGFLERLSETSGGMFVGLMAFLLSFYLIFTNEGRALKTATSLAEGLSLVVSPDSIHSVAPE--NE 85
            |||||||..::||:..|...|.||.|::||||||||:.|.:|.||||.:|...|  ...||  |:
Zfish    12 PGFLERLRASTGGVIAGACLFALSLYVLFTNEGRALRIAAALDEGLSQLVCVQS--DAQPELRND 74

Human    86 GRLVHIIGALRTSKLLSDPNYGVHLPAVKLRRHVEMYQWVETEESREYTEDGQVKKETRYSYTDT 150
            |||||:.|.|||::.|.||||.|.:.||||:|.||||||||..:||...|:|:.|.||.||| :|
Zfish    75 GRLVHLSGDLRTAQPLHDPNYSVSVHAVKLQRQVEMYQWVEYSDSRTVEENGEKKTETTYSY-NT 138

Human   151 EWRSEIINSKNFDREIGHKNPSAMAVESFMATAPFVQIGRFFLSSGLIDKVDNFKSLSLSKLEDP 215
            |||||:|:|::||:|:||.|||.|||||....||.|.:|.|.||:||::::..|.:||||.|..|
Zfish   139 EWRSEVISSRHFDQEVGHMNPSEMAVESVTVVAPEVWVGNFLLSTGLVEQISEFHTLSLSALPVP 203

Human   216 HVDIIR-RGDFFYHSENPKYPEVGDLRVSFSYAGLSGDDPDLGPAHVVTVIARQRGDQLVPFSTK 279
            ....:. :.|::||:.||::|||||:||.|:|||||||....|.||.|:|:|:|...||.|||::
Zfish   204 VAGFLTVQDDYYYHTPNPRHPEVGDVRVRFAYAGLSGDGLYPGSAHKVSVVAQQHQQQLRPFSSR 268

Human   280 SGDTLLLLHHGDFSAEEVFHRELRSNSMKTWGLRAAGWMAMFMGLNLMTRILYTLVDWFPVFRDL 344
            ||.||.||:.|..:|||:|.:|.:.||||||.||.||...||:.::|.||:::|||:..|:...|
Zfish   269 SGHTLELLYMGQLTAEELFAKEHQLNSMKTWALRLAGCTLMFLSISLSTRVIHTLVERVPLLGGL 333

Human   345 VNIGLKAFAFCVATSLTLLTVAAGWLFYRPLWALLIAGLALV-PILVARTRVPAKK 399
            :::||:.|..|.:.||:|||:||||::||||.||.:|..||| |:.:|..|.||||
Zfish   334 LSVGLQLFCLCSSISLSLLTIAAGWIYYRPLLALCVAAAALVLPLALAHARAPAKK 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TMEM43	NP_001394203.1	TMEM43	121..374	CDD:462267	131/253 (52%)
tmem43	NP_001427784.1	None