DRSC/TRiP Functional Genomics Resources

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Protein Alignment TMEM43 and tmem43

DIOPT Version :10

Sequence 1:NP_001394203.1 Gene:TMEM43 / 79188 HGNCID:28472 Length:401 Species:Homo sapiens
Sequence 2:XP_002938277.1 Gene:tmem43 / 100495534 XenbaseID:XB-GENE-961649 Length:398 Species:Xenopus tropicalis


Alignment Length:390 Identity:241/390 - (61%)
Similarity:313/390 - (80%) Gaps:1/390 - (0%)


- Green bases have known domain annotations that are detailed below.


Human    12 REHVKVKTSSQPGFLERLSETSGGMFVGLMAFLLSFYLIFTNEGRALKTATSLAEGLSLVVSPDS 76
            :||..|::..:||||||||:|:|||.|||:||.|||||:|||||||::|||||.||||:||...:
 Frog    10 KEHTTVRSEQKPGFLERLSDTAGGMLVGLLAFSLSFYLLFTNEGRAVQTATSLDEGLSIVVPVGN 74

Human    77 IHSVAPENEGRLVHIIGALRTSKLLSDPNYGVHLPAVKLRRHVEMYQWVETEESREYTEDGQVKK 141
            |||:..:||..|||:.|||||||.|.||||||.:..|||:|.||||||:|.||||:|.|:|:.|.
 Frog    75 IHSIDHQNEANLVHLSGALRTSKPLYDPNYGVSIHCVKLKRQVEMYQWIEYEESRQYEENGEQKT 139

Human   142 ETRYSYTDTEWRSEIINSKNFDREIGHKNPSAMAVESFMATAPFVQIGRFFLSSGLIDKVDNFKS 206
            ||||:| :|||||||::|::|||||.|:||||||||||.|.:..||:|.::||.||:||:||||.
 Frog   140 ETRYTY-NTEWRSEIVSSRHFDREIAHQNPSAMAVESFTAVSSDVQVGSYYLSKGLVDKIDNFKQ 203

Human   207 LSLSKLEDPHVDIIRRGDFFYHSENPKYPEVGDLRVSFSYAGLSGDDPDLGPAHVVTVIARQRGD 271
            :|||:|.:||.|:|..|.:||||.|||.|||||||:||.|||::......|...:|:|||||||.
 Frog   204 MSLSQLGNPHADVIADGGYFYHSANPKSPEVGDLRISFWYAGVALGGAQFGQPDMVSVIARQRGG 268

Human   272 QLVPFSTKSGDTLLLLHHGDFSAEEVFHRELRSNSMKTWGLRAAGWMAMFMGLNLMTRILYTLVD 336
            :|..:.|||||.|.|||.|.:||:|:|..|.:||::|||.||.|||:.||:|::|||:|.|||||
 Frog   269 ELGAYKTKSGDVLELLHMGTYSAQEMFEAEHKSNNLKTWALRGAGWLMMFVGISLMTKIFYTLVD 333

Human   337 WFPVFRDLVNIGLKAFAFCVATSLTLLTVAAGWLFYRPLWALLIAGLALVPILVARTRVPAKKLE 401
            |||:.||||::|||..|.||::||:|||:||||:|||||.|||::..|:..|::||:|||.||.:
 Frog   334 WFPLVRDLVSLGLKICALCVSSSLSLLTIAAGWIFYRPLLALLLSAAAIGIIVLARSRVPPKKYQ 398

Human   402  401
             Frog   399  398

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TMEM43NP_001394203.1 TMEM43 121..374 CDD:462267 155/252 (62%)
tmem43XP_002938277.1 TMEM43 119..371 CDD:462267 155/252 (62%)

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