back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment TTPAL and CG5958

DIOPT Version :10

Sequence 1:	NP_077307.2	Gene:	TTPAL / 79183	HGNCID:	16114	Length:	342	Species:	Homo sapiens
Sequence 2:	NP_609119.2	Gene:	CG5958 / 34022	FlyBaseID:	FBgn0031913	Length:	294	Species:	Drosophila melanogaster

Alignment Length:	282	Identity:	93/282 - (32%)
Similarity:	148/282 - (52%)	Gaps:	9/282 - (3%)

- Green bases have known domain annotations that are detailed below.

Human    30 GYVCSLTEDLVTKAREELQEKPEWRLRDVQALRDMVRKEYPNLSTSLDDAFLLRFLRARKFDYDR 94
            ||   |..:.|..||.||:|..|.:...:..||::: |..|.|:...|||||..||||..|..:.
  Fly    16 GY---LKPETVEIARVELRETEEVKAEAIIKLRELL-KATPELNYKDDDAFLTVFLRACHFYPEG 76

Human    95 ALQLLVNYHSCRRSWPEVFNNLKPSALKDVLASG-FLTVLPHTDPRGCHVVCIRPDR-WIPSNYP 157
            ||:.:....|.|:.:..:...|....:|:....| .:.||.:.|.:|..|:.:...: |.||:..
  Fly    77 ALEKMKTTASFRKEYASLVRGLLVEQVKEKFVKGSVINVLKNCDQKGRRVLIVNCGKLWDPSDIT 141

Human   158 ITENIRAIYLTLEKLIQSEETQVNGIVILADYKGVSLSKASHFGPFIAKKVIGILQDGFPIRIKA 222
            ..|..|.:|:........|||||.|:|.:.|::|:|:.:.....|..:|:::..:|:..|:|:|.
  Fly   142 SDEMFRMLYMVHLAAQLEEETQVRGVVCIMDFEGLSMKQVKALSPSFSKRLLTFIQEAMPLRMKE 206

Human   223 VHVVNEPRIFKGIFAIIKPFLKEKIANRFFLHGSDLNSLHTNLPRSILPKEYGGTAGELD--TAT 285
            ||.|.:|.||..::::.|||:|:|:.||...||||:.||...|..|:||..|.||...:|  ...
  Fly   207 VHFVKQPFIFNMVWSLFKPFVKQKLNNRMHFHGSDMKSLQKFLDPSVLPANYKGTLPAIDYGGVE 271

Human   286 WNAVLLASEDDFVKEFCQPVPA 307
            |... |..:..:|:|:.|..||
  Fly   272 WFPA-LEQQAQYVEEWSQLGPA 292

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.