Protein Alignment TMEM185B and CG14194

DIOPT Version :10

• Sequence 1: NP_077026.2
• Gene: TMEM185B / 79134
• HGNCID: 18896
• Length: 350
• Species: Homo sapiens
• Sequence 2: NP_573360.1
• Gene: CG14194 / 32908
• FlyBaseID: FBgn0030996
• Length: 358
• Species: Drosophila melanogaster
• Alignment Length: 362
• Identity: 164/362 - (45%)
• Similarity: 230/362 - (63%)
• Gaps: 16/362 - (4%)

Human     1 MNPRGLFQDFNPSKFLIYTCLLLFSVLLPLRLDGIIQWSYWAVFAPIWLWKLLVVAGASVGAGVW 65
            ||...||:||||.||:::..|.:|..|..||||..|.|.|||:|.|:|:||...:.||.|||.||
  Fly     1 MNLESLFRDFNPCKFIVHCSLFIFVTLFALRLDNYIDWPYWAIFTPLWIWKCTAILGAIVGAIVW 65

Human    66 ARNPRYRTEGEACVEFKAMLIAVGIHLLLLMFEVLVCDRVERGTHFWLLVFMPLFFVSPVSVAAC 130
            .|.|.||.||:|..:||||||::.:||:|||||:|.||::....|.|:|||:||.|.|.|||.||
  Fly    66 CRYPHYRLEGDAYTQFKAMLISLALHLILLMFELLACDKLTSDRHLWVLVFIPLIFGSVVSVGAC 130

Human   131 VWGFRHDRSLELEILCSVNILQFIFIALKLDRIIHWPWLVVFVPLWILMSFLCLVVLYYIVWSLL 195
            ||..:||||.|||:..:||.|||:.:.|||||.::|.|.|||||:||::....:.|||.|::..:
  Fly   131 VWAVKHDRSFELELFLAVNALQFVSLPLKLDRFVYWNWDVVFVPMWIVICLSLVSVLYNIIFCGI 195

Human   196 FLRSLDVVAEQRRTHVTMAISWITIVVPLLTFEVLLVHRLDGHNTFSYVSIFVPLWLSLLTLMAT 260
            .:|:.:|..:|::..:..|:..|..|:|||.|:|::..:|||...|.|:.:|.||.:|:|.|:..
  Fly   196 MMRTPEVSLQQKKAALNAAVGNICTVLPLLCFQVVICDKLDGELKFPYIVVFSPLLVSILALIVL 260

Human   261 TFRRKGGNHWWFGIRRDFCQFLLEIFPFLREYGNISYDLHHEDSEDAEE----------TSVPEA 315
            :...||||.||||||:.|.||||...|||:|||||||  |.|...:|.:          ||:..:
  Fly   261 SSSAKGGNMWWFGIRKSFSQFLLSAMPFLQEYGNISY--HPETHSNAAQSMPLDAASSSTSMAAS 323

Human   316 PKIAPI--FGKKARVVITQSPGKYVPPPPKLNIDMPD 350
            .::...  ..||::........|  |..|.::||:||
  Fly   324 EQLHEFHKHDKKSKKGAKNDILK--PVVPFVSIDLPD 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TMEM185B	NP_077026.2	Tmemb_185A	31..253	CDD:402059	108/221 (49%)
CG14194	NP_573360.1	Tmemb_185A	30..253	CDD:402059	109/222 (49%)