Protein Alignment REEP5 and CG4960

DIOPT Version :10

• Sequence 1: NP_005660.4
• Gene: REEP5 / 7905
• HGNCID: 30077
• Length: 189
• Species: Homo sapiens
• Sequence 2: NP_651429.1
• Gene: CG4960 / 43115
• FlyBaseID: FBgn0039371
• Length: 174
• Species: Drosophila melanogaster
• Alignment Length: 143
• Identity: 72/143 - (50%)
• Similarity: 94/143 - (65%)
• Gaps: 4/143 - (2%)

Human    20 TDLLAKLEAKTGVNRSFIALGVIGLVALYLVFGYGASLLCNLIGFGYPAYISIKAIESPNKEDDT 84
            |.....||.||||.|..|.:|.|...|.|||||:.|.||||:||..|||||||..|||..|:||.
  Fly    31 TKAFDSLEEKTGVERVNIFVGSILFCAFYLVFGWCAQLLCNIIGVLYPAYISIHGIESSTKQDDI 95

Human    85 QWLTYWVVYGVFSIAEFFSDIFLSWFPFYYMLKCGFLLWCMAPSPSNGAELLYKRIIRPFFLKHE 149
            :||.|||.:|:|::.||:..:..|..|||::|||.||:|||.|:..||:.|:|.:::||:|||..
  Fly    96 RWLIYWVTFGIFTVIEFYPSLLTSMIPFYWLLKCTFLIWCMLPTERNGSTLIYHKLVRPYFLKLH 160

Human   150 SQMD----SVVKD 158
            ..:|    .|.||
  Fly   161 DPVDMMSAGVPKD 173

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
REEP5	NP_005660.4	TB2_DP1_HVA22	67..144	CDD:460820	39/76 (51%)
		Required for dimerization and maintaining endoplasmic reticulum morphology. /evidence=ECO:0000269|PubMed:32075961	114..185		22/49 (45%)
CG4960	NP_651429.1	TB2_DP1_HVA22	78..155	CDD:460820	39/76 (51%)