Protein Alignment REEP5 and ReepB

DIOPT Version :10

• Sequence 1: NP_005660.4
• Gene: REEP5 / 7905
• HGNCID: 30077
• Length: 189
• Species: Homo sapiens
• Sequence 2: NP_610936.2
• Gene: ReepB / 36569
• FlyBaseID: FBgn0033906
• Length: 178
• Species: Drosophila melanogaster
• Alignment Length: 144
• Identity: 76/144 - (52%)
• Similarity: 106/144 - (73%)
• Gaps: 0/144 - (0%)

Human    20 TDLLAKLEAKTGVNRSFIALGVIGLVALYLVFGYGASLLCNLIGFGYPAYISIKAIESPNKEDDT 84
            |.:...:|.||||:|..|.:|.:||.|:||:||:||.||||:||..|||||||.||||..|:|||
  Fly    28 TKVFDTVEEKTGVDRVNIFVGAVGLCAIYLIFGWGAQLLCNIIGVLYPAYISIHAIESSTKQDDT 92

Human    85 QWLTYWVVYGVFSIAEFFSDIFLSWFPFYYMLKCGFLLWCMAPSPSNGAELLYKRIIRPFFLKHE 149
            :||.|||.:|:|::.||||.:..|..|||::|||.||:|||.|:..||:.::|.:::||:||||.
  Fly    93 KWLIYWVTFGIFTVIEFFSSLLTSVIPFYWLLKCAFLIWCMLPTEQNGSTIIYNKLVRPYFLKHH 157

Human   150 SQMDSVVKDLKDKA 163
            ..:|.::.|...||
  Fly   158 ESVDRIIDDGMKKA 171

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
REEP5	NP_005660.4	TB2_DP1_HVA22	67..144	CDD:460820	42/76 (55%)
		Required for dimerization and maintaining endoplasmic reticulum morphology. /evidence=ECO:0000269|PubMed:32075961	114..185		22/50 (44%)
ReepB	NP_610936.2	TB2_DP1_HVA22	75..152	CDD:460820	42/76 (55%)