Protein Alignment ST8SIA4 and SiaT

DIOPT Version :10

• Sequence 1: NP_005659.1
• Gene: ST8SIA4 / 7903
• HGNCID: 10871
• Length: 359
• Species: Homo sapiens
• Sequence 2: NP_523853.1
• Gene: SiaT / 37950
• FlyBaseID: FBgn0035050
• Length: 474
• Species: Drosophila melanogaster
• Alignment Length: 338
• Identity: 81/338 - (23%)
• Similarity: 131/338 - (38%)
• Gaps: 80/338 - (23%)

Human     9 TICTIS--LLLIFYKTKEIARTEEHQETQLIGDGELSLSRSLVNSSDKIIRKAGSSIFQHNV--- 68
            |..|:|  |.|...|..|:...:..|..|.|   ..:..:::|.|.::      |....:||
  Fly   129 TKLTLSPKLYLCHDKHSELCHNKTQQFRQRI---VRAFEKAMVESVNE------SQANHYNVDYK 184

Human    69 --------EGWKINSSLVLEIRKNILRFLDAERDVSVVKSSFKPGDVIHYVLDRRRTLNISHDLH 125
                    |.:..::.||:|....:||..||            |.:.:.:              .
  Fly   185 PVFGDSFEEQYYPSTCLVMEAGVRVLRRKDA------------PFNKLPF--------------G 223

Human   126 SLLPEVSPMKN-RRFKTCAVVGNSGILLDSECGKEIDSHNFVIRCNLAPVVEFAADVGTKSDFIT 189
            .|.|.....:| :..||||:|.::|.|..|:.|:.||:|:.|:|.|.||......|||:|:....
  Fly   224 RLFPRQKLFRNVKDIKTCAIVSSAGSLAGSKLGRFIDTHDIVMRFNHAPTQGHEVDVGSKTTIRV 288

Human   190 MNPSVVQRAFGGFRNESDREKFVHRLSMLNDSV-LWIPAFMVKGGEKHVEWVNAL---ILKNKLK 250
            :|..||.:.      |.|   |.......|.:: .|.|.   |......:|:.:.   :..|...
  Fly   289 VNSQVVTKP------EFD---FTRAPIFRNVTIAAWDPG---KYNGTLEDWLTSADYDLFSNYEL 341

Human   251 VRTAYPSLRLI----HAVRGYWLTNKV-----PIKR--PSTGLLMYTLATRFCDEIHLYGFWPFP 304
            .|..||..|..    |:|...|.:.::     ||.:  ||:|.:...|....|.::....:.|..
  Fly   342 YRRRYPKSRAFLIDPHSVWRLWQSLQMFAGNRPISKNPPSSGFIGLALLLPHCPQVDFVEYVPST 406

Human   305 KDLNGKAVKYHYY 317
            : |||:.   |||
  Fly   407 R-LNGRC---HYY 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ST8SIA4	NP_005659.1	GT29_ST8SIA4	76..353	CDD:467716	65/258 (25%)
SiaT	NP_523853.1	GT29_ST6GAL1_2	199..469	CDD:467696	65/259 (25%)