Protein Alignment SPATA5L1 and RIX7

DIOPT Version :9

• Sequence 1: NP_076968.2
• Gene: SPATA5L1 / 79029
• HGNCID: 28762
• Length: 753
• Species: Homo sapiens
• Sequence 2: NP_013066.1
• Gene: RIX7 / 850625
• SGDID: S000003957
• Length: 837
• Species: Saccharomyces cerevisiae
• Alignment Length: 667
• Identity: 229/667 - (34%)
• Similarity: 345/667 - (51%)
• Gaps: 129/667 - (19%)

Human   181 RTRVSLGGEPPSEAQPQPEVPLGGLSEAADSLRELLRLPLRYPRALTALGLAVPRGVLLAGPPGV 245
            |.::.....||:.:...    |||:.:....|.||:.||:.:|....:.|:..||||||.||||.
Yeast   190 RQKIKEDRSPPNSSLKS----LGGMDDVVAQLMELIGLPILHPEIFLSTGVEPPRGVLLHGPPGC 250

Human   246 GKTQLVRAVAREAGAELLAVSAPALQGSRPGETEENVRRVFQRARELASRGPSLLFLDEMDALCP 310
            |||.:..|:|.|.....:::|||::.....||:|:.:|.:|..||.||   |.|:|.||:||:.|
Yeast   251 GKTSIANALAGELQVPFISISAPSVVSGMSGESEKKIRDLFDEARSLA---PCLVFFDEIDAITP 312

Human   311 QR---GSRAPESRVVAQVLTLLD----GASGDREVVVVGATNRPDALDPALRRPGRFDREVVIGT 368
            :|   ..|..|.|:|||:||.:|    ..:..:.|:::|||||||:||.||||.||||||:.:..
Yeast   313 KRDGGAQREMERRIVAQLLTSMDELTMEKTNGKPVIIIGATNRPDSLDAALRRAGRFDREICLNV 377

Human   369 PTLKQRKEILQVITSKMPISSHVDLGLLAEMTVGYVGADLTALCREAAMHALLH----------- 422
            |....|..||:.::..:.|...:|...||::|.|:|||||.||...|...|:..
Yeast   378 PNEVSRLHILKKMSDNLKIDGAIDFAKLAKLTPGFVGADLKALVTAAGTCAIKRIFQTYANIKST 442

Human   423 ----SEKNQDNPVIDEI-----------------------------------------------D 436
                ::.::||..|||.                                               |
Yeast   443 PTTATDSSEDNMEIDETANGDESSLKNTANMIDPLPLSVVQQFIRNYPEPLSGEQLSLLSIKYED 507

Human   437 FLEAFKNIQPSSFRSVIGLMDIKPVDWEEIGGLEDVKLKLKQSIEWPLKFPWEFVRMGLTQPKGV 501
            ||:|...|||::.|.  |...:..|.|..:|.|:.|:|:|..:|..|:|.|..:.::|::.|.||
Yeast   508 FLKALPTIQPTAKRE--GFATVPDVTWANVGALQRVRLELNMAIVQPIKRPELYEKVGISAPGGV 570

Human   502 LLYGPPGCAKTTLVRALATSCHCSFVSVSGADLFSPFVGDSEKVLSQIFRQARASTPAILFLDEI 566
            ||:|||||.||.|.:|:|.....:|:|:.|.:|.:.:||:||:.:.|:|.:||||.|.::|.||:
Yeast   571 LLWGPPGCGKTLLAKAVANESRANFISIKGPELLNKYVGESERSIRQVFTRARASVPCVIFFDEL 635

Human   567 DSILGARSASKTGCDVQERVLSVLLNELDGVGLKTIERRGSKSSQQEFQEVFNRSVMIIAATNRP 631
            |:::..|..|.:  :...||::.||.||||:.    :|||               :.:|.|||||
Yeast   636 DALVPRRDTSLS--ESSSRVVNTLLTELDGLN----DRRG---------------IFVIGATNRP 679

Human   632 DVLDTALLRPGRLDKIIYIPPPDHKGRLSILKVCTKT--MPIGPDVSLENLAA-ETC-FFSGADL 692
            |::|.|:||||||||.::|..|:.:.:|.|:|..||:  .|:..||..|.:.. |.| .||||||
Yeast   680 DMIDPAMLRPGRLDKSLFIELPNTEEKLDIIKTLTKSHGTPLSSDVDFEEIIRNEKCNNFSGADL 744

Human   693 RNLCTEAALLALQ-------------ENGLD-------------ATTVKQEHFLKSLKTVKPSLS 731
            ..|..|:::|||:             :|.||             ...|....|..:|:.:|||:|
Yeast   745 AALVRESSVLALKRKFFQSEEIQSVLDNDLDKEFEDLSVGVSGEEIIVTMSDFRSALRKIKPSVS 809

Human   732 CKDLALYENLFKKEGFS 748
            .||...|:.|.||.|.:
Yeast   810 DKDRLKYDRLNKKMGLT 826

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SPATA5L1	NP_076968.2	CDC48	22..746	CDD:273521	228/663 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	171..203		3/21 (14%)
		AAA	237..367	CDD:278434	63/136 (46%)
		AAA	501..651	CDD:278434	62/149 (42%)
RIX7	NP_013066.1	CDC48	<192..824	CDD:273521	227/661 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000137
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810