DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Birc3 and Bruce

DIOPT Version :9

Sequence 1:	NP_076477.3	Gene:	Birc3 / 78971	RGDID:	621282	Length:	638	Species:	Rattus norvegicus
Sequence 2:	NP_001262460.1	Gene:	Bruce / 41260	FlyBaseID:	FBgn0266717	Length:	4976	Species:	Drosophila melanogaster

Alignment Length:	147	Identity:	50/147 - (34%)
Similarity:	71/147 - (48%)	Gaps:	29/147 - (19%)

- Green bases have known domain annotations that are detailed below.

  Rat   202 MNTEKARLLTYQTWP---LSFLSPAELAKAGFYY---TGPGDRVACFACGGKLSNWDRKDDPLSE 260
            |::|..|..|::.||   ..:..|.::|:||||:   :...||..||.|...|..|::.|:|.||
  Fly   245 MHSEAVRRQTFEKWPHMDYKWALPDQMAQAGFYHQPSSSGEDRAMCFTCSVCLVCWEKTDEPWSE 309

  Rat   261 HRRHFPSCPFLKDVGQFTSQYTVSNLSMQTHAARVRTFSTWPSSALVHPQELASAGFYYTGHSD- 324
            |.||.|.|||:|  |::|....:|           .|::|.|  ||..|    ..||....:||
  Fly   310 HERHSPLCPFVK--GEYTQNVPLS-----------ITYATNP--ALPAP----GLGFDIISNSDY 355

  Rat   325 -DVKCFCCD--GGLRCW 338
             :|.|..|.  |.|..|
  Fly   356 ANVLCTSCSQTGELSVW 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Birc3	NP_076477.3	BIR	68..133	CDD:395528
		BIR	206..272	CDD:237989	28/71 (39%)
		BIR	290..358	CDD:197595	16/53 (30%)
		UBA_BIRC2_3	412..461	CDD:270577
		DD	476..564	CDD:417479
		RING-HC_BIRC2_3_7	585..638	CDD:319627
Bruce	NP_001262460.1	BIR	251..321	CDD:279047	28/69 (41%)
		DUF3643	3539..3664	CDD:289152
		UQ_con	4636..4790	CDD:278603
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810