Protein Alignment KCNAB1 and CG18547

DIOPT Version :10

• Sequence 1: NP_751892.1
• Gene: KCNAB1 / 7881
• HGNCID: 6228
• Length: 419
• Species: Homo sapiens
• Sequence 2: NP_650138.1
• Gene: CG18547 / 41452
• FlyBaseID: FBgn0037973
• Length: 345
• Species: Drosophila melanogaster
• Alignment Length: 343
• Identity: 88/343 - (25%)
• Similarity: 151/343 - (44%)
• Gaps: 55/343 - (16%)

Human    89 MPHRNLGKSGLRVSCLGLGTWVTFGG-----QISDEVAERLMTI--AYESGVNLFDTAEVYAAGK 146
            |.:|||||:||:||      .|:|||     ....::.|.:.|:  |.:||:|..|||..|..|:
  Fly    22 MEYRNLGKTGLQVS------KVSFGGGALCANYGFDLEEGIKTVHEAVKSGINYIDTAPWYGQGR 80

Human   147 AEVILGSIIKKKGWRRSSLVITTKLYWGGKAETER----GLSRKHIIEGLKGSLQRLQLEYVDVV 207
            :|.:||..:|..  .|.|..|.||:   .:.|.:.    ..|.|...|.::.||:.|.|:||||:
  Fly    81 SEEVLGLALKDV--PRESYYIATKV---ARYELDYDKMFDFSAKKTRESVEKSLKLLGLDYVDVI 140

Human   208 ------FANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQ 266
                  ||.  |.:..:.|.:..:..::.:|.|.:.|.|.:....:.|  .:.|....:..|...
  Fly   141 QIHDIEFAK--DLDIVINETLPTLEQLVKEGKARFIGVSAYPISVLKE--FLTRTAGRLDTVLTY 201

Human   267 AEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLKCYQWLKERIVS 331
            |.|.|  .::..::..:.:....:|.:..:..|.|:::    |..|:         .|   ...|
  Fly   202 ARYTL--TDETLLEYLDFFKSQNLGVICAAAHALGLLT----NAGPQ---------PW---HPAS 248

Human   332 EEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRN-EGVSSVLLGSSTPEQLIENLGAIQV-LPK 394
            :|   |:...:..|.:.:..|..|.:||:.:.:.. ..||:.|.|..|.:.|..||.|.:| |..
  Fly   249 DE---QKAIARKASEVCKERGVELGKLAMYYTMSGLPEVSTFLTGMQTRQLLRINLDANEVGLSD 310

Human   395 MTSHVVNEIDNILRNKPY 412
            ....|:..:...:..||:
  Fly   311 KEQEVLRYLKENVLTKPF 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KCNAB1	NP_751892.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..52
		AKR_KCAB1B_AKR6A3-like	89..411	CDD:381385	86/340 (25%)
CG18547	NP_650138.1	AKR_galDH	22..314	CDD:381389	85/327 (26%)