Protein Alignment KCNAB1 and CG2767

DIOPT Version :10

• Sequence 1: NP_751892.1
• Gene: KCNAB1 / 7881
• HGNCID: 6228
• Length: 419
• Species: Homo sapiens
• Sequence 2: NP_649757.1
• Gene: CG2767 / 40946
• FlyBaseID: FBgn0037537
• Length: 329
• Species: Drosophila melanogaster
• Alignment Length: 344
• Identity: 84/344 - (24%)
• Similarity: 142/344 - (41%)
• Gaps: 82/344 - (23%)

Human    97 SGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKKGW- 160
            :|.::..:|:|||     |.|||..|..:..|.|:|....|||.||...||   :|.::|:  |
  Fly    11 NGEKMPVIGIGTW-----QASDEEIETAIDAALEAGYRHIDTAPVYGNEKA---IGRVLKR--WL 65

Human   161 -----RRSSLVITTKLYWGGKAETERGLSRKHIIE-GLKGSLQRLQLEYVDVVFANRP------- 212
                 :|..|.|.||:        ....:|.|.:| .:|.||:.|||:|||:...:.|
  Fly    66 DAGKVKREELFIVTKV--------PPVSNRPHEVEPTIKKSLEDLQLDYVDLYLVHTPFTININE 122

Human   213 --------------DSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPV 263
                          |..|....|..||..::.:|:....|.|.:|..::.......:    |.|.
  Fly   123 DGSFKLDKEGLMEVDVTTNHAAIWVAMEALVEKGLTKSIGVSNFSKDQVARLLKNCK----IRPA 183

Human   264 CEQAEYHLF--QREKVEVQLPELYHKIGVGAMTWSPLAC-GIISGKYGNGVPESSRASLKCYQWL 325
            ..|.|:|::  ||:.|:....|     .:....:|||.. ||.....|.|:...          |
  Fly   184 NNQIEHHVYLQQRDLVDFCKSE-----NITVTAYSPLGSKGIAKFNAGAGIVRD----------L 233

Human   326 KERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSSTPEQLIENLGAIQ 390
            .:.:          .:.::..||...|.|..|:.:.|.: :.|||:: ..|:.|.:|.:||....
  Fly   234 PDLM----------DIPEVKEIAASHGKTPAQVLLRWII-DTGVSAI-PKSTNPARLKQNLDVFD 286

Human   391 VLPKMTSHVVNEIDNILRN 409
            .  ::|:..|.::.::.:|
  Fly   287 F--ELTAEEVAKLSSLDQN 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KCNAB1	NP_751892.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..52
		AKR_KCAB1B_AKR6A3-like	89..411	CDD:381385	84/344 (24%)
CG2767	NP_649757.1	AKR_AKR1I_CgAKR1	4..309	CDD:381381	84/344 (24%)