Protein Alignment KCNAB1 and CG12766

DIOPT Version :10

• Sequence 1: NP_751892.1
• Gene: KCNAB1 / 7881
• HGNCID: 6228
• Length: 419
• Species: Homo sapiens
• Sequence 2: NP_647839.1
• Gene: CG12766 / 38462
• FlyBaseID: FBgn0035476
• Length: 320
• Species: Drosophila melanogaster
• Alignment Length: 334
• Identity: 73/334 - (21%)
• Similarity: 130/334 - (38%)
• Gaps: 89/334 - (26%)

Human    98 GLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKK---- 158
            |..:..:||||:.:..|.     .||.:..|.:.|....|||..| ..:|||  |:.::||
  Fly    14 GTHIQGIGLGTFASTEGD-----CERAVLHAIDVGYRHIDTAYFY-GNEAEV--GAAVRKKIAEG 70

Human   159 GWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRP----------- 212
            ..:|..:.||||| |....|.||      :....:.:|:.:.|:|||:...:.|
  Fly    71 VIKREDIFITTKL-WCNFHEPER------VEYACRKTLKNIGLDYVDLYLIHWPFSYKYRGDNEL 128

Human   213 ---DSNTPME-------EIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQA 267
               |:|..:|       :...||..:::.|:....|.|.::..::....:..:    |.|:..|.
  Fly   129 IPKDANGEVELVDIDYLDTWGAMEKLVDLGLTKSIGVSNFNEEQLTRLLANCK----IKPIHNQI 189

Human   268 EYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLKCYQWLKERIVSE 332
            |.|....:|   :|..|..|.|:....:|||      |::        .|.|:...::      .
  Fly   190 EVHPALDQK---KLIALCKKNGILVTAFSPL------GRH--------NAELRTPTFM------Y 231

Human   333 EGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLG------SSTPEQLIENLGAIQV 391
            :|:.|        .||::...::.|:.:.:.:.        ||      ||.|:::.||......
  Fly   232 DGKVQ--------AIADKYNKSIAQVVIRYVIE--------LGTIPLPKSSNPKRIEENFNVFDF 280

Human   392 LPKMTSHVV 400
            ......|.:
  Fly   281 KLDAEDHAI 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KCNAB1	NP_751892.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..52
		AKR_KCAB1B_AKR6A3-like	89..411	CDD:381385	73/334 (22%)
CG12766	NP_647839.1	AKR_AKR2E1-5	7..299	CDD:381342	73/334 (22%)