Protein Alignment RAB7A and Rab7

DIOPT Version :10

• Sequence 1: NP_004628.4
• Gene: RAB7A / 7879
• HGNCID: 9788
• Length: 207
• Species: Homo sapiens
• Sequence 2: NP_524472.1
• Gene: Rab7 / 42841
• FlyBaseID: FBgn0015795
• Length: 207
• Species: Drosophila melanogaster
• Alignment Length: 207
• Identity: 158/207 - (76%)
• Similarity: 182/207 - (87%)
• Gaps: 0/207 - (0%)

Human     1 MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTA 65
            |:.|||.||||||||||.|||||||||||||:|||||||||||||.||||:|:||:|||||||||
  Fly     1 MSGRKKSLLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTA 65

Human    66 GQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLE 130
            ||||||||||||||||||||||:||||||:||.|||||||||||||||||::|||||||||:||:
  Fly    66 GQERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDLD 130

Human   131 NRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDKN 195
            ||||:|:|||.||.|||:|||:||||||.||||.|||.||:|||:.|.|.|:.|:||:.|.|...
  Fly   131 NRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNALELEAEAEVINDFPDQITLGSQ 195

Human   196 DRAKASAESCSC 207
            :....:.::|.|
  Fly   196 NNRPGNPDNCQC 207

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB7A	NP_004628.4	Rab7	9..179	CDD:206655	144/169 (85%)
		Switch 1. /evidence=ECO:0000269|PubMed:15933719, ECO:0007744|PDB:1T91, ECO:0007744|PDB:1YHN	28..41		11/12 (92%)
		Switch 2. /evidence=ECO:0000269|PubMed:15933719, ECO:0007744|PDB:1T91, ECO:0007744|PDB:1YHN	67..82		14/14 (100%)
Rab7	NP_524472.1	Rab7	9..179	CDD:206655	144/169 (85%)