Protein Alignment RAB7A and Rab30

DIOPT Version :10

• Sequence 1: NP_004628.4
• Gene: RAB7A / 7879
• HGNCID: 9788
• Length: 207
• Species: Homo sapiens
• Sequence 2: NP_609094.1
• Gene: Rab30 / 33988
• FlyBaseID: FBgn0031882
• Length: 223
• Species: Drosophila melanogaster
• Alignment Length: 172
• Identity: 67/172 - (38%)
• Similarity: 105/172 - (61%)
• Gaps: 7/172 - (4%)

Human     6 KVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERF 70
            |.|.|::::|::|||||.|:.::....|.....||||.||:.|.|.|:...:.:|||||||||||
  Fly     5 KFLFKIVLVGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEVEGEKIKLQIWDTAGQERF 69

Human    71 QSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVA 135
            :|:..::||.|...:||:|::...||..|..|..|....|:.:..:    :::|||.|.::|::.
  Fly    70 RSITQSYYRSAHALILVYDISCQPTFDCLPDWLREIQEYANSKVLK----ILVGNKTDRDDREIP 130

Human   136 TKRAQAWCYSKNNIPYF-ETSAKEAINVEQAFQTIARNALKQ 176
            |:..:.  ::|.:..|| |||||||.|||:.|..||...:.|
  Fly   131 TQIGEE--FAKQHDMYFLETSAKEAENVERLFYEIAAELIGQ 170

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB7A	NP_004628.4	Rab7	9..179	CDD:206655	65/169 (38%)
		Switch 1. /evidence=ECO:0000269|PubMed:15933719, ECO:0007744|PDB:1T91, ECO:0007744|PDB:1YHN	28..41		2/12 (17%)
		Switch 2. /evidence=ECO:0000269|PubMed:15933719, ECO:0007744|PDB:1T91, ECO:0007744|PDB:1YHN	67..82		7/14 (50%)
Rab30	NP_609094.1	Rab30	1..168	CDD:133314	66/168 (39%)