| Sequence 1: | NP_003459.2 | Gene: | FZD5 / 7855 | HGNCID: | 4043 | Length: | 585 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_004917802.1 | Gene: | fzd5 / 100488110 | XenbaseID: | XB-GENE-479707 | Length: | 559 | Species: | Xenopus tropicalis |
| Alignment Length: | 574 | Identity: | 427/574 - (74%) |
|---|---|---|---|
| Similarity: | 479/574 - (83%) | Gaps: | 26/574 - (4%) |
- Green bases have known domain annotations that are detailed below.
|
Human 12 LLLLLLAQLVGRAAAASKAPVCQEITVPMCRGIGYNLTHMPNQFNHDTQDEAGLEVHQFWPLVEI 76
Human 77 QCSPDLRFFLCSMYTPICLPDYHKPLPPCRSVCERAKAGCSPLMRQYGFAWPERMSCDRLPVLGR 141
Human 142 DAEVLCMDYNRSEATTAPPRPFPAKPTLPGPPGAPASGGECPAGGPFVCKCREPFVPILKESHPL 206
Human 207 YNKVRTGQVPNCAVPCYQPSFSADERTFATFWIGLWSVLCFISTSTTVATFLIDMERFRYPERPI 271
Human 272 IFLSACYLCVSLGFLVRLVVGHASVACSREHNHIHYETTGPALCTIVFLLVYFFGMASSIWWVIL 336
Human 337 SLTWFLAAGMKWGNEAIAGYAQYFHLAAWLIPSVKSITALALSSVDGDPVAGICYVGNQNLNSLR 401
Human 402 GFVLGPLVLYLLVGTLFLLAGFVSLFRIRSVIKQGGTKTDKLEKLMIRIGIFTLLYTVPASIVVA 466
Human 467 CYLYEQHYRESWEAALTCACPGHDTGQPRAKPEYWVLMLKYFMCLVVGITSGVWIWSGKTVESWR 531
Human 532 RFTSRCCCRPRRGHKSGGAMAAGDYPEASAALTGRTGPPGPAATYHKQVSLSHV 585 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| FZD5 | NP_003459.2 | TM helix 5 | 397..426 | CDD:320377 | 21/28 (75%) |
| TM helix 6 | 446..473 | CDD:320377 | 22/26 (85%) | ||
| TM helix 7 | 496..521 | CDD:320377 | 19/24 (79%) | ||
| Lys-Thr-X-X-X-Trp motif, mediates interaction with the PDZ domain of Dvl family members. /evidence=ECO:0000250 | 525..530 | 3/4 (75%) | |||
| PDZ-binding | 583..585 | 1/1 (100%) | |||
| CRD_FZ5 | 29..156 | CDD:143569 | 107/126 (85%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 156..179 | 8/22 (36%) | |||
| 7tmF_FZD5 | 225..535 | CDD:320377 | 252/309 (82%) | ||
| TM helix 1 | 234..259 | CDD:320377 | 22/24 (92%) | ||
| TM helix 2 | 268..289 | CDD:320377 | 16/20 (80%) | ||
| TM helix 3 | 316..342 | CDD:320377 | 21/25 (84%) | ||
| TM helix 4 | 359..375 | CDD:320377 | 14/15 (93%) | ||
| fzd5 | XP_004917802.1 | CRD_FZ5 | 29..153 | CDD:143569 | 106/124 (85%) |
| 7tmF_FZD5 | 212..517 | CDD:320377 | 252/309 (82%) | ||
| TM helix 1 | 221..246 | CDD:320377 | 22/24 (92%) | ||
| TM helix 2 | 255..276 | CDD:320377 | 16/20 (80%) | ||
| TM helix 3 | 301..327 | CDD:320377 | 21/25 (84%) | ||
| TM helix 4 | 344..360 | CDD:320377 | 14/15 (93%) | ||
| TM helix 5 | 382..411 | CDD:320377 | 21/28 (75%) | ||
| TM helix 6 | 431..458 | CDD:320377 | 22/26 (85%) | ||
| TM helix 7 | 478..503 | CDD:320377 | 19/24 (79%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 536 | 1.000 | Domainoid score | I3166 |
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H2590 | |
| Inparanoid | 1 | 1.050 | 875 | 1.000 | Inparanoid score | I3852 |
| NCBI | 1 | 1.000 | - | - | ||
| OMA | 1 | 1.010 | - | - | QHG49270 | |
| OrthoDB | 1 | 1.010 | - | - | D105541at32523 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0003114 | |
| OrthoInspector | 1 | 1.000 | - | - | oto158024 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR11309 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R4396 |
| SonicParanoid | 1 | 1.000 | - | - | X126 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 14 | 14.110 | |||||