| Sequence 1: | NP_001334985.1 | Gene: | CXCR4 / 7852 | HGNCID: | 2561 | Length: | 423 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_476701.1 | Gene: | Rh4 / 39887 | FlyBaseID: | FBgn0003250 | Length: | 378 | Species: | Drosophila melanogaster |
| Alignment Length: | 319 | Identity: | 69/319 - (21%) |
|---|---|---|---|
| Similarity: | 123/319 - (38%) | Gaps: | 74/319 - (23%) |
- Green bases have known domain annotations that are detailed below.
|
Human 112 LPTIYSIIFLTGIVGNGLVILVMGYQKKLRSMTDKYRLHLSVADLLFVITLPFWAVDAVANWY-F 175
Human 176 GNFLCKAVHVIYTVNLYSSV---LILAFISLDRYLAIVHATNSQRPRKLLAEKVVYVG--VWI-- 233
Human 234 -PALLLTIPDFIFANVSEADDRYI-------CDRFYPND-----LWV-VVFQFQHIMVGLILPGI 284
Human 285 VILSCYCIIISKL-SHSKGHQKR----------------------KALKTTVILILAFFACWLPY 326
Human 327 YIGISIDSFILLEIIKQGCEFENTVHKWISITEALAFFHCCLNPILYAFLGAKFKTSAQ 385 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CXCR4 | NP_001334985.1 | CXCR4_N | 77..109 | CDD:314911 | |
| 7tmA_CXCR4 | 110..384 | CDD:320307 | 68/316 (22%) | ||
| TM helix 1 | 110..137 | CDD:320307 | 9/24 (38%) | ||
| TM helix 2 | 144..169 | CDD:320307 | 6/24 (25%) | ||
| TM helix 3 | 180..210 | CDD:320307 | 8/32 (25%) | ||
| TM helix 4 | 222..244 | CDD:320307 | 5/26 (19%) | ||
| TM helix 5 | 267..296 | CDD:320307 | 8/29 (28%) | ||
| TM helix 6 | 303..333 | CDD:320307 | 6/51 (12%) | ||
| TM helix 7 | 352..377 | CDD:320307 | 5/24 (21%) | ||
| Rh4 | NP_476701.1 | 7tmA_photoreceptors_insect | 55..345 | CDD:320207 | 68/316 (22%) |
| TM helix 1 | 57..81 | CDD:320207 | 9/23 (39%) | ||
| TM helix 2 | 90..111 | CDD:320207 | 6/20 (30%) | ||
| TM helix 3 | 127..149 | CDD:320207 | 4/24 (17%) | ||
| TM helix 4 | 170..186 | CDD:320207 | 2/15 (13%) | ||
| TM helix 5 | 215..238 | CDD:320207 | 7/27 (26%) | ||
| TM helix 6 | 279..301 | CDD:320207 | 6/21 (29%) | ||
| TM helix 7 | 313..338 | CDD:320207 | 6/33 (18%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||