| Sequence 1: | NP_036425.1 | Gene: | PXDN / 7837 | HGNCID: | 14966 | Length: | 1479 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_006515268.1 | Gene: | Pxdn / 69675 | MGIID: | 1916925 | Length: | 1503 | Species: | Mus musculus |
| Alignment Length: | 1479 | Identity: | 1322/1479 - (89%) |
|---|---|---|---|
| Similarity: | 1377/1479 - (93%) | Gaps: | 28/1479 - (1%) |
- Green bases have known domain annotations that are detailed below.
|
Human 1 MAKRSRGPGRRCLLALVLFCAWGTLAVVAQKPGAGCPSRCLCFRTTVRCMHLLLEAVPAVAPQTS 65
Human 66 ILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSIDRQAF 130
Human 131 KGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKRLRLDSNTLH 195
Human 196 CDCEILWLADLLKTYAESGNAQAAAICEYPRRIQGRSVATITPEELNCERPRITSEPQDADVTSG 260
Human 261 NTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLMIQNTQETDQGIYQCMAKNVAGE 325
Human 326 VKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTRGDRTPLPVDPRVN 390
Human 391 ITPSGGLYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCE 455
Human 456 AKGNPPPVIAWTKGGSQLSVDRRHLVLSSGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQ 520
Human 521 PRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPEGFLTINDVG 585
Human 586 PADAGRYECVARNTIGSASVSMVLSVNVPDVSRNGDPFVATSIVEAIATVDRAINSTRTHLFDSR 650
Human 651 PRSPNDLLALFRYPRDPYTVEQARAGEIFERTLQLIQEHVQHGLMVDLNGTSYHYNDLVSPQYLN 715
Human 716 LIANLSGCTAHRRVNNCSDMCFHQKYRTHDGTCNNLQHPMWGASLTAFERLLKSVYENGFNTPRG 780
Human 781 INPHRLYNGHALPMPRLVSTTLIGTETVTPDEQFTHMLMQWGQFLDHDLDSTVVALSQARFSDGQ 845
Human 846 HCSNVCSNDPPCFSVMIPPNDSRARSGARCMFFVRSSPVCGSGMTSLLMNSVYPREQINQLTSYI 910
Human 911 DASNVYGSTEHEARSIRDLASHRGLLRQGIVQRSGKPLLPFATGPPTECMRDENESPIPCFLAGD 975
Human 976 HRANEQLGLTSMHTLWFREHNRIATELLKLNPHWDGDTIYYETRKIVGAEIQHITYQHWLPKILG 1040
Human 1041 EVGMRTLGEYHGYDPGINAGIFNAFATAAFRFGHTLVNPLLYRLDENFQPIAQDHLPLHKAFFSP 1105
Human 1106 FRIVNEGGIDPLLRGLFGVAGKMRVPSQLLNTELTERLFSMAHTVALDLAAINIQRGRDHGIPPY 1170
Human 1171 HDYRVYCNLSAAHTFEDLKNEIKNPEIREKLKRLYGSTLNIDLFPALVVEDLVPGSRLGPTLMCL 1235
Human 1236 LSTQFKRLRDGDRLWYENPGVFSPAQLTQIKQTSLARILCDNADNITRVQSDVFRVAEFPHGYGS 1300
Human 1301 CDEIPRVDLRVWQDCCEDCRTRGQFNAFSYHFRGRRSLEFSYQEDKPTKKTRPRKIPSVGRQGEH 1365
Human 1366 LSNSTSAFSTRSDASGTNDFREFVLEMQKTITDLRTQIKKLESRLSTTECVDAGGESHANNTKWK 1430
Human 1431 KDACTICECKDGQVTCFVEACPPATCAVPVNIPGACCPVCLQKRAEEKP 1479 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| PXDN | NP_036425.1 | leucine-rich repeat | 45..63 | CDD:275380 | 17/17 (100%) |
| LRR 1. /evidence=ECO:0000255 | 61..84 | 22/22 (100%) | |||
| leucine-rich repeat | 66..87 | CDD:275380 | 20/20 (100%) | ||
| LRR 2. /evidence=ECO:0000255 | 85..108 | 19/22 (86%) | |||
| LRR | <97..>215 | CDD:443914 | 86/117 (74%) | ||
| LRR 3. /evidence=ECO:0000255 | 110..132 | 5/21 (24%) | |||
| leucine-rich repeat | 112..135 | CDD:275378 | 3/22 (14%) | ||
| LRR 4. /evidence=ECO:0000255 | 133..156 | 15/22 (68%) | |||
| leucine-rich repeat | 136..159 | CDD:275378 | 18/22 (82%) | ||
| LRR 5. /evidence=ECO:0000255 | 157..180 | 22/22 (100%) | |||
| leucine-rich repeat | 160..183 | CDD:275378 | 20/22 (91%) | ||
| LRR 6. /evidence=ECO:0000255 | 182..204 | 20/21 (95%) | |||
| leucine-rich repeat | 184..196 | CDD:275378 | 10/11 (91%) | ||
| LRRCT | 192..243 | CDD:214507 | 47/50 (94%) | ||
| I-set | 246..333 | CDD:400151 | 82/86 (95%) | ||
| Ig strand B | 263..267 | CDD:409490 | 3/3 (100%) | ||
| Ig strand C | 276..280 | CDD:409490 | 3/3 (100%) | ||
| Ig strand F | 314..319 | CDD:409490 | 3/4 (75%) | ||
| Ig strand G | 328..331 | CDD:409490 | 2/2 (100%) | ||
| I-set | 342..429 | CDD:400151 | 74/86 (86%) | ||
| Ig strand B | 359..363 | CDD:409544 | 3/3 (100%) | ||
| Ig strand C | 372..376 | CDD:409544 | 1/3 (33%) | ||
| Ig strand E | 395..399 | CDD:409544 | 3/3 (100%) | ||
| Ig strand F | 409..414 | CDD:409544 | 3/4 (75%) | ||
| Ig strand G | 422..425 | CDD:409544 | 2/2 (100%) | ||
| Ig3_Peroxidasin | 446..519 | CDD:143222 | 69/72 (96%) | ||
| Ig strand B | 450..454 | CDD:143222 | 3/3 (100%) | ||
| Ig strand C | 463..467 | CDD:143222 | 3/3 (100%) | ||
| Ig strand E | 485..489 | CDD:143222 | 3/3 (100%) | ||
| Ig strand F | 499..504 | CDD:143222 | 4/4 (100%) | ||
| Ig strand G | 513..516 | CDD:143222 | 2/2 (100%) | ||
| Ig4_Peroxidasin | 542..610 | CDD:143223 | 65/67 (97%) | ||
| Ig strand B | 542..546 | CDD:143223 | 3/3 (100%) | ||
| Ig strand C | 555..559 | CDD:143223 | 3/3 (100%) | ||
| Ig strand E | 577..581 | CDD:143223 | 3/3 (100%) | ||
| Ig strand F | 591..596 | CDD:143223 | 4/4 (100%) | ||
| Ig strand G | 605..608 | CDD:143223 | 2/2 (100%) | ||
| peroxidasin_like | 864..1303 | CDD:188658 | 410/438 (94%) | ||
| LRR 7. /evidence=ECO:0000255 | 1151..1175 | 23/23 (100%) | |||
| LRR 8. /evidence=ECO:0000255 | 1270..1291 | 18/20 (90%) | |||
| Required in homotrimerization. /evidence=ECO:0000269|PubMed:31295557 | 1315..1411 | 68/95 (72%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1342..1380 | 19/37 (51%) | |||
| VWC | 1415..1470 | CDD:214564 | 39/54 (72%) | ||
| Pxdn | XP_006515268.1 | leucine-rich repeat | 94..112 | CDD:275380 | 17/17 (100%) |
| leucine-rich repeat | 113..127 | CDD:275378 | 13/13 (100%) | ||
| LRR_8 | 160..219 | CDD:404697 | 55/82 (67%) | ||
| leucine-rich repeat | 161..184 | CDD:275378 | 21/46 (46%) | ||
| leucine-rich repeat | 185..208 | CDD:275378 | 20/22 (91%) | ||
| leucine-rich repeat | 209..221 | CDD:275378 | 10/11 (91%) | ||
| LRRCT | 217..268 | CDD:214507 | 47/50 (94%) | ||
| I-set | 271..358 | CDD:400151 | 82/86 (95%) | ||
| Ig strand B | 288..292 | CDD:409353 | 3/3 (100%) | ||
| Ig strand C | 301..305 | CDD:409353 | 3/3 (100%) | ||
| Ig strand F | 339..344 | CDD:409353 | 3/4 (75%) | ||
| Ig strand G | 353..356 | CDD:409353 | 2/2 (100%) | ||
| I-set | 367..454 | CDD:400151 | 74/86 (86%) | ||
| Ig strand B | 384..388 | CDD:409353 | 3/3 (100%) | ||
| Ig strand C | 397..401 | CDD:409353 | 1/3 (33%) | ||
| Ig strand E | 420..424 | CDD:409353 | 3/3 (100%) | ||
| Ig strand F | 434..439 | CDD:409353 | 3/4 (75%) | ||
| Ig strand G | 447..450 | CDD:409353 | 2/2 (100%) | ||
| Ig3_Peroxidasin | 471..544 | CDD:143222 | 69/72 (96%) | ||
| Ig strand B | 475..479 | CDD:143222 | 3/3 (100%) | ||
| Ig strand C | 488..492 | CDD:143222 | 3/3 (100%) | ||
| Ig strand E | 510..514 | CDD:143222 | 3/3 (100%) | ||
| Ig strand F | 524..529 | CDD:143222 | 4/4 (100%) | ||
| Ig strand G | 538..541 | CDD:143222 | 2/2 (100%) | ||
| Ig4_Peroxidasin | 567..635 | CDD:143223 | 65/67 (97%) | ||
| Ig strand B | 567..571 | CDD:143223 | 3/3 (100%) | ||
| Ig strand C | 580..584 | CDD:143223 | 3/3 (100%) | ||
| Ig strand E | 602..606 | CDD:143223 | 3/3 (100%) | ||
| Ig strand F | 616..621 | CDD:143223 | 4/4 (100%) | ||
| Ig strand G | 630..633 | CDD:143223 | 2/2 (100%) | ||
| peroxidasin_like | 889..1328 | CDD:188658 | 410/438 (94%) | ||
| VWC | 1439..1494 | CDD:214564 | 39/54 (72%) |