| Sequence 1: | NP_036425.1 | Gene: | PXDN / 7837 | HGNCID: | 14966 | Length: | 1479 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_505188.3 | Gene: | pxn-1 / 191484 | WormBaseID: | WBGene00004256 | Length: | 1285 | Species: | Caenorhabditis elegans |
| Alignment Length: | 1336 | Identity: | 498/1336 - (37%) |
|---|---|---|---|
| Similarity: | 704/1336 - (52%) | Gaps: | 146/1336 - (10%) |
- Green bases have known domain annotations that are detailed below.
|
Human 13 LLALVLFCAWGTLAVVAQKPGAGCPSRCLCFR--TTVRCMHLLLEAVPA-VAPQTSILDLRFNRI 74
Human 75 REIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSIDR--QAFKGLASLE 137
Human 138 QLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKRLRLDSNTLHCDCEILW 202
Human 203 LADLLKTYAESGNAQAAAICEYPRRIQGRSVATITPEELNCERPRITSEPQDADVTSGNTVYFTC 267
Human 268 RAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLMIQNTQETDQGIYQCMAKNVAGEVKTQEVT 332
Human 333 LRYFGSPARPTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPSGGL 397
Human 398 YIQNVVQGDSGEYACSATNNIDSVHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPP 462
Human 463 VIAWTKGGSQ-LSVDRRHLVLSSGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTPV 526
Human 527 FASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTE-SGKFHISPEGF-LTINDVGPADA 589
Human 590 GRYECVARNTIGSASVSMVLSVNVPDVSRNGDPFVATSIVEAIA-----TVDRAINSTRTHLFDS 649
Human 650 RPRSPNDLLALFRYPRDPYTVEQARAGEIFERTLQLIQEHVQHGLMV---DLNGTSYHYNDLVSP 711
Human 712 QYLNLIANLSGCTAHRRVNNCSDMCFHQKYRTHDGTCNNLQHPMWGASLTAFERLLKSVYENGFN 776
Human 777 TPRGINPHRLYNGHALPMPRLVSTTLIGTETVTPDEQFTHMLMQWGQFLDHDLDSTVVALSQARF 841
Human 842 SDGQHCSNVCSNDPPCFSVMIPPNDSRARSGAR---CMFFVRSSPVCGSGMTSLLMNSVYPREQI 903
Human 904 NQLTSYIDASNVYGSTEHEARSIRDLASHRGLLRQGIVQRSGKPLLPFATGPPTECMRD-ENESP 967
Human 968 IPCFLAGDHRANEQLGLTSMHTLWFREHNRIATELLKLNPHWDGDTIYYETRKIVGAEIQHITYQ 1032
Human 1033 HWLPKILGEVGM--RTLGEYHGYDPGINAGIFNAFATAAFRFGHTLVNPLLYRLDENFQPIAQDH 1095
Human 1096 LPLHKAFFSPFRIVNEGGIDPLLRGLFGVAGKMRVPSQLLNTELTERLFSMAHTVALDLAAINIQ 1160
Human 1161 RGRDHGIPPYHDYRVYCNLSAAHTFEDLKNEIKNPEIREKLKRLYGSTLNIDLFPALVVEDLVPG 1225
Human 1226 SRLGPTLMCLLSTQFKRLRDGDRLWYENPGVFSPAQLTQIKQTSLARILCDNADNITRVQSDVFR 1290
Human 1291 VAEFP----HGYGSCDEIPRVDLRVWQDCCED-CRT 1321 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| PXDN | NP_036425.1 | leucine-rich repeat | 45..63 | CDD:275380 | 4/18 (22%) |
| leucine-rich repeat | 66..87 | CDD:275380 | 5/20 (25%) | ||
| LRR 1 | 87..108 | 8/20 (40%) | |||
| LRR_4 | 110..151 | CDD:289563 | 14/42 (33%) | ||
| LRR_8 | 111..170 | CDD:290566 | 19/60 (32%) | ||
| LRR 2 | 111..132 | 7/22 (32%) | |||
| leucine-rich repeat | 112..135 | CDD:275378 | 8/24 (33%) | ||
| LRR_4 | 135..175 | CDD:289563 | 13/39 (33%) | ||
| LRR 3 | 135..156 | 6/20 (30%) | |||
| leucine-rich repeat | 136..159 | CDD:275378 | 5/22 (23%) | ||
| LRR_8 | 158..>195 | CDD:290566 | 12/36 (33%) | ||
| LRR 4 | 159..180 | 7/20 (35%) | |||
| leucine-rich repeat | 160..183 | CDD:275378 | 8/22 (36%) | ||
| leucine-rich repeat | 184..196 | CDD:275378 | 3/11 (27%) | ||
| TPKR_C2 | 192..243 | CDD:301599 | 10/50 (20%) | ||
| Ig | 246..333 | CDD:299845 | 11/86 (13%) | ||
| I-set | 246..333 | CDD:254352 | 11/86 (13%) | ||
| I-set | 342..429 | CDD:254352 | 11/86 (13%) | ||
| Ig | 346..429 | CDD:299845 | 10/82 (12%) | ||
| I-set | 433..519 | CDD:254352 | 35/86 (41%) | ||
| Ig3_Peroxidasin | 446..519 | CDD:143222 | 29/73 (40%) | ||
| I-set | 525..611 | CDD:254352 | 27/87 (31%) | ||
| Ig4_Peroxidasin | 542..610 | CDD:143223 | 23/69 (33%) | ||
| An_peroxidase | 741..1282 | CDD:281139 | 289/546 (53%) | ||
| peroxidasin_like | 864..1303 | CDD:188658 | 235/448 (52%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1342..1380 | ||||
| VWC | 1415..1470 | CDD:214564 | |||
| pxn-1 | NP_505188.3 | LRRNT | 23..51 | CDD:279764 | 8/27 (30%) |
| leucine-rich repeat | 35..53 | CDD:275380 | 4/17 (24%) | ||
| LRR_8 | 52..112 | CDD:290566 | 19/59 (32%) | ||
| LRR_4 | 53..93 | CDD:289563 | 13/39 (33%) | ||
| leucine-rich repeat | 54..77 | CDD:275380 | 5/22 (23%) | ||
| LRR_4 | 77..120 | CDD:289563 | 16/42 (38%) | ||
| leucine-rich repeat | 78..101 | CDD:275380 | 9/22 (41%) | ||
| leucine-rich repeat | 102..117 | CDD:275380 | 7/14 (50%) | ||
| LRR_8 | 123..182 | CDD:290566 | 19/61 (31%) | ||
| leucine-rich repeat | 125..148 | CDD:275380 | 8/25 (32%) | ||
| leucine-rich repeat | 149..172 | CDD:275380 | 8/22 (36%) | ||
| I-set | 315..400 | CDD:254352 | 34/84 (40%) | ||
| IGc2 | 328..392 | CDD:197706 | 27/63 (43%) | ||
| IG_like | 414..496 | CDD:214653 | 26/81 (32%) | ||
| Ig | 420..496 | CDD:299845 | 25/75 (33%) | ||
| An_peroxidase | 634..1181 | CDD:281139 | 289/546 (53%) | ||
| peroxidasin_like | 757..1203 | CDD:188658 | 235/448 (52%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C161458102 | |
| Domainoid | 1 | 1.000 | 606 | 1.000 | Domainoid score | I101 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG2408 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H33907 | |
| Inparanoid | 1 | 1.050 | 795 | 1.000 | Inparanoid score | I275 |
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S3260 |
| OMA | 1 | 1.010 | - | - | QHG46064 | |
| OrthoDB | 1 | 1.010 | - | - | D276568at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000202 | |
| OrthoInspector | 1 | 1.000 | - | - | mtm4964 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_105829 | |
| Panther | 1 | 1.100 | - | - | O | PTHR11475 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R2739 |
| SonicParanoid | 1 | 1.000 | - | - | X2950 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| 17 | 16.750 | |||||