| Sequence 1: | XP_005271230.1 | Gene: | LRP8 / 7804 | HGNCID: | 6700 | Length: | 976 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_011238756.1 | Gene: | Lrp8 / 16975 | MGIID: | 1340044 | Length: | 1010 | Species: | Mus musculus |
| Alignment Length: | 1018 | Identity: | 875/1018 - (85%) |
|---|---|---|---|
| Similarity: | 911/1018 - (89%) | Gaps: | 50/1018 - (4%) |
- Green bases have known domain annotations that are detailed below.
|
Human 1 MGLPEPGPLRLLALLLLLLLLLLLQLQHLAAAAADPLLGGQGPAKDCEKDQFQCRNERCIPSVWR 65
Human 66 CDEDDDCLDHSDEDDCPKKTCADSDFTCDNGHCIHERWKCDGEEECPDGSDESEATCTKQVCPAE 130
Human 131 KLSCGPTSHKCVPASWRCDGEKDCEGGADEAGCATLCAPHEFQCGNRSCLAAVFVCDGDDDCGDG 195
Human 196 SDERGCADPACGPREFRCGGDGGGACIPERWVCDRQFDCEDRSDEAAELCGRPGPGATSAPAACA 260
Human 261 TASQFACRSGECVHLGWRCDGDRDCKDKSDEADCPL-GTCRGDEFQCGDGTCVLAIKHCNQEQDC 324
Human 325 PDGSDEAGCLQ-----------------------------------------VPPTFLGNRRRPR 348
Human 349 GLNECLHNNGGCSHICTDLKIGFECTCPAGFQLLDQKTCGDIDECKDPDACSQICVNYKGYFKCE 413
Human 414 CYPGYEMDLLTKNCKAAAGKSPSLIFTNRHEVRRIDLVKRNYSRLIPMLKNVVALDVEVATNRIY 478
Human 479 WCDLSYRKIYSAYMDKASDPKEQEVLIDEQLHSPEGLAVDWVHKHIYWTDSGNKTISVATVDGGR 543
Human 544 RRTLFSRNLSEPRAIAVDPLRGFMYWSDWGDQAKIEKSGLNGVDRQTLVSDNIEWPNGITLDLLS 608
Human 609 QRLYWVDSKLHQLSSIDFSGGNRKTLISSTDFLSHPFGIAVFEDKVFWTDLENEAIFSANRLNGL 673
Human 674 EISILAENLNNPHDIVIFHELKQPRAPDACELSVQPNGGCEYLCLPAPQISSHSPKYTCACPDTM 738
Human 739 WLGPDMKRCYRAPQSTSTTTLASTMTRTVPATTRAPGTTVHRSTYQNHSTETPSLTAAVPSSVSV 803
Human 804 PRAPSISPSTLSPATSNHSQHYANEDSKMGSTVTAAVIGIIVPIVVIALLCMSGYLIWRNWKRKN 868
Human 869 TKSMNFDNPVYRKTTEEEDEDELHIGRTAQIGHVYPAAISSFDRPLWAEPCLGETREPEDPAPAL 933
Human 934 KELFVLPGEPRSQLHQLPKNPLSELPVVKSKRVALSLEDDGLP 976 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| LRP8 | XP_005271230.1 | LDLa | 47..81 | CDD:238060 | 27/33 (82%) |
| LDLa | 85..117 | CDD:197566 | 30/31 (97%) | ||
| LDLa | 127..163 | CDD:238060 | 35/35 (100%) | ||
| LDLa | 206..240 | CDD:197566 | 29/33 (88%) | ||
| Ldl_recept_a | 262..294 | CDD:278486 | 27/31 (87%) | ||
| Ldl_recept_a | 298..333 | CDD:278486 | 29/34 (85%) | ||
| FXa_inhibition | 353..387 | CDD:291342 | 33/33 (100%) | ||
| EGF_CA | 389..419 | CDD:214542 | 27/29 (93%) | ||
| LY | 458..493 | CDD:214531 | 33/34 (97%) | ||
| LY | 502..544 | CDD:214531 | 38/41 (93%) | ||
| Ldl_recept_b | 565..605 | CDD:278487 | 36/39 (92%) | ||
| LY | 589..631 | CDD:214531 | 40/41 (98%) | ||
| Ldl_recept_b | 652..691 | CDD:278487 | 37/38 (97%) | ||
| FXa_inhibition | 710..747 | CDD:291342 | 36/36 (100%) | ||
| Lrp8 | XP_011238756.1 | LDLa | 41..75 | CDD:238060 | 27/33 (82%) |
| LDLa | 79..111 | CDD:197566 | 30/31 (97%) | ||
| LDLa | 121..157 | CDD:238060 | 35/35 (100%) | ||
| LDLa | 200..232 | CDD:197566 | 29/33 (88%) | ||
| LDLa | 256..286 | CDD:238060 | 27/29 (93%) | ||
| LDLa | 292..326 | CDD:238060 | 29/33 (88%) | ||
| LDLa | 330..366 | CDD:381805 | 0/35 (0%) | ||
| FXa_inhibition | 387..421 | CDD:373209 | 33/33 (100%) | ||
| EGF_CA | 423..453 | CDD:214542 | 27/29 (93%) | ||
| LY | 492..527 | CDD:214531 | 33/34 (97%) | ||
| LY | 537..578 | CDD:214531 | 38/40 (95%) | ||
| Ldl_recept_b | 599..639 | CDD:278487 | 36/39 (92%) | ||
| LY | 623..665 | CDD:214531 | 40/41 (98%) | ||
| Ldl_recept_b | 686..725 | CDD:278487 | 37/38 (97%) | ||
| FXa_inhibition | 744..781 | CDD:373209 | 36/36 (100%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C83971830 | |
| Domainoid | 1 | 1.000 | 544 | 1.000 | Domainoid score | I6348 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG1215 | |
| HGNC | 1 | 1.500 | - | - | ||
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H31250 | |
| Inparanoid | 1 | 1.050 | 1628 | 1.000 | Inparanoid score | I2523 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| NCBI | 1 | 1.000 | - | - | ||
| OMA | 1 | 1.010 | - | - | QHG49125 | |
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0002088 | |
| OrthoInspector | 1 | 1.000 | - | - | oto125096 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_103130 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR24270 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R7933 |
| SonicParanoid | 1 | 1.000 | - | - | X1052 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| 17 | 17.290 | |||||