Protein Alignment DDR1 and CG3277

DIOPT Version :10

• Sequence 1: XP_054186331.1
• Gene: DDR1 / 780
• HGNCID: 2730
• Length: 984
• Species: Homo sapiens
• Sequence 2: NP_608762.3
• Gene: CG3277 / 33543
• FlyBaseID: FBgn0031518
• Length: 789
• Species: Drosophila melanogaster
• Alignment Length: 377
• Identity: 107/377 - (28%)
• Similarity: 168/377 - (44%)
• Gaps: 100/377 - (26%)

Human   622 DFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGH-PLLVAVKILRPD--ATKNA 683
            :.|.|.::....||||.||:||....            :|:|:.. ..:||||.|:|:  |.:.|
  Fly   420 EVPHSAIQIGRMLGEGAFGQVHEATA------------INLRRMRGTTIVAVKQLKPNPKADEVA 472

Human   684 SFSLFSRNDFLKEVKIMSRL-KDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFL-----SAHQL 742
                    ::|.|::::..: ...|::..||.|....|..||.:|:..|:|..:|     .|.:|
  Fly   473 --------EYLAEIEMLKGVGTHHNVVSFLGCCTIKPPYLMIMEYVNKGNLLSYLRTVRKEASKL 529

Human   743 EDKAAE--------------GAPGDGQA------AQGPTISYPM--------------------- 766
            .::.|.              .:|.....      |...||..|.
  Fly   530 RNRNANYTSCRPIMTRTNSTSSPKSQSVNYIELKASSQTIEMPQEDSTAHMNGIRQPHPSFAETT 594

Human   767 ------------------LLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSR 813
                              |.:.|.|||:|||:|......|||||.||.|:..|.|:||:|||:||
  Fly   595 YTIVEDEDAFEYILDNKELHNFALQIANGMRFLEEQEITHRDLAARNVLIDSNKTLKISDFGLSR 659

Human   814 NLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVI 878
            :   |.|...:.|. ||:||::.|.|....:::.||:||:||.|||:..| .|.|:..::::::|
  Fly   660 H---GIYTNTRTRK-LPLRWLSIEAIRENVYSSKSDIWAYGVVLWEIGTL-GASPYPTISNDELI 719

Human   879 ENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLA 930
            .     |...|.:  |.||..|...:|.:||:||..|.|:||.|..|::.|:
  Fly   720 P-----FLMAGNR--LERPEICTPQVYTIMLQCWLEEPEERPTFDALYKVLS 764

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DDR1	XP_054186331.1	FA58C	78..202	CDD:238014
		PTKc_DDR1	622..931	CDD:133227	107/377 (28%)
CG3277	NP_608762.3	PTKc	430..763	CDD:270623	104/364 (29%)