DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment odad2 and p120ctn

DIOPT Version :9

Sequence 1:	NP_001072494.1	Gene:	odad2 / 779949	XenbaseID:	XB-GENE-982927	Length:	1053	Species:	Xenopus tropicalis
Sequence 2:	NP_001036444.1	Gene:	p120ctn / 3355143	FlyBaseID:	FBgn0260799	Length:	781	Species:	Drosophila melanogaster

Alignment Length:	696	Identity:	146/696 - (20%)
Similarity:	244/696 - (35%)	Gaps:	238/696 - (34%)

- Green bases have known domain annotations that are detailed below.

Frog   389 KNTKDEKKDPSKKPTS---------SESRQRTNAHSVVRRSALKSKTPGAKSDEFSESSTESEED 444
            :||....|..|.:|.:         ::|:.||      .:|:.:.|.|     :|:.||..:
  Fly   147 QNTTSSIKPFSGRPFNDNINGAEAVADSQCRT------FKSSAEFKLP-----QFAMSSINT--- 197

Frog   445 EEQPERRQEGNTDLPSEYWQIQKLVKYLKGGNQTATVIALCSI---RDFNLAQETCQLAIRDVGG 506
              .|:|.:|.:              .|::|....     :||.   ||.||::
  Fly   198 --VPQRLEEKD--------------DYIEGSEND-----ICSTMRWRDPNLSE------------ 229

Frog   507 LDILINLLNTEEIKCKIGALKILKEISHNSQIRSAIADLGGLQTMVGILDSQDKDLKCLAAETIA 571
               :|:.|:......|..|...|:.:.:                    :|..:|
  Fly   230 ---VISFLSNPSSAIKANAAAYLQHLCY--------------------MDDPNK----------- 260

Frog   572 NVAKFRRARRTVRQHGGIRRLVGLLDCAPIGSSNLSAQQEKDIEVARCGALALWSCSK-STRNKE 635
                    :|| |..|||..||.||           :....:|....||||...|..: :..||.
  Fly   261 --------QRT-RSLGGIPPLVRLL-----------SYDSPEIHKNACGALRNLSYGRQNDENKR 305

Frog   636 AIRKAGGIPLLARLL-KSSHSNMLIPVVGTLQECASEPSYRLAIKTEKMIEDLVKNLKSENPELQ 699
            .|:.||||..|..|| :|..:.:...|.|.|...:|....:.:|..|.::..:...:|.
  Fly   306 GIKNAGGIAALVHLLCRSQETEVKELVTGVLWNMSSCEDLKRSIIDEALVAVVCSVIKP------ 364

Frog   700 MH-----------CASAIFKCAEDEETRDLVRQYGGLQPLAMLLGQFENKELLAAVTGAIWKCSI 753
             |           |.|.:|:.|.     .::|........|.  |...|.|.|......:.:.||
  Fly   365 -HSGWDAVCCGETCFSTVFRNAS-----GVLRNVSSAGEHAR--GCLRNCEHLVECLLYVVRTSI 421

Frog   754 SRDNVTKFQEYKVIETLVTLLTN-------------------QPEEVLVNVVGALGECGQEPANR 799
            .::|:..    |.:|..|.:|.|                   .||.|:.:  .:.||
  Fly   422 EKNNIGN----KTVENCVCILRNLSYRCQEVDDPNYDKHPFITPERVIPS--SSKGE-------- 472

Frog   800 AIIRKCGGISPLVNL-LSGTN----QALLVNVTKAVGACASDPENMVIIDRLD-GVRLLW----- 853
                         || ..|||    :|...:........|...::.|..::|: |...||
  Fly   473 -------------NLGCFGTNKKKKEANNSDALNEYNISADYSKSSVTYNKLNKGYEQLWQPEVV 524

Frog   854 ----SLLKN-PHPDVQANAAWAI-----C---PCIENAKDAGEMVRSFV---GGLELIVNLLKSE 902
                |||:: .:|:....||.||     |   |.|:        :|:.|   .||.::|.||:.|
  Fly   525 QYYLSLLQSCSNPETLEAAAGAIQNLSACYWQPSID--------IRATVRKEKGLPILVELLRME 581

Frog   903 NKEVLASVCAAITNIAKDEENLAVITDHGVVALLSAL--------ANTTDDKLRRHLA---EAIS 956
            ...|:.:|..|:.|:|.|:.|..:|..:.:..|:..|        .||:||.:...||   |.|.
  Fly   582 VDRVVCAVATALRNLAIDQRNKELIGKYAMRDLVQKLPSGNVQHDQNTSDDTITAVLATINEVIK 646

Frog   957 RCCMWGHNRVAFGESKAVAPLVHYLKSSD---PLVHRATAQALYQL 999
            :...:..:.:   :|..:..|::..|..:   ..|.:..:|.||.:
  Fly   647 KNPEFSRSLL---DSGGIDRLMNITKRKEKYTSCVLKFASQVLYTM 689

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
odad2	NP_001072494.1	armadillo repeat	465..490	CDD:293788	5/27 (19%)
		ARM	499..602	CDD:237987	17/102 (17%)
		armadillo repeat	500..532	CDD:293788	5/31 (16%)
		armadillo repeat	539..573	CDD:293788	2/33 (6%)
		armadillo repeat	583..626	CDD:293788	13/42 (31%)
		armadillo repeat	634..670	CDD:293788	13/36 (36%)
		ARM	635..749	CDD:237987	27/125 (22%)
		armadillo repeat	675..707	CDD:293788	6/42 (14%)
		ARM	717..830	CDD:237987	25/136 (18%)
		armadillo repeat	719..750	CDD:293788	6/30 (20%)
		armadillo repeat	767..791	CDD:293788	7/42 (17%)
		armadillo repeat	799..835	CDD:293788	6/40 (15%)
		armadillo repeat	840..872	CDD:293788	13/47 (28%)
		ARM	843..957	CDD:237987	41/146 (28%)
		HEAT_2	851..956	CDD:290374	38/136 (28%)
		armadillo repeat	882..917	CDD:293788	11/37 (30%)
		ARM	924..1040	CDD:237987	18/90 (20%)
		armadillo repeat	924..956	CDD:293788	10/42 (24%)
		HEAT_2	932..1034	CDD:290374	17/82 (21%)
		armadillo repeat	1007..1040	CDD:293788
p120ctn	NP_001036444.1	ARM	227..341	CDD:237987	38/179 (21%)
		armadillo repeat	227..252	CDD:293788	6/39 (15%)
		armadillo repeat	260..296	CDD:293788	16/66 (24%)
		armadillo repeat	304..339	CDD:293788	13/34 (38%)
		ARM	307..442	CDD:237987	35/152 (23%)
		armadillo repeat	347..392	CDD:293788	9/56 (16%)
		armadillo repeat	515..556	CDD:293788	11/40 (28%)
		ARM	516..643	CDD:237987	37/134 (28%)
		armadillo repeat	562..596	CDD:293788	11/33 (33%)
		armadillo repeat	601..641	CDD:293788	10/39 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2332
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940