DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rnf145 and sip3

DIOPT Version :9

Sequence 1:	NP_001072260.1	Gene:	rnf145 / 779713	XenbaseID:	XB-GENE-979193	Length:	695	Species:	Xenopus tropicalis
Sequence 2:	NP_001263152.1	Gene:	sip3 / 43747	FlyBaseID:	FBgn0039875	Length:	626	Species:	Drosophila melanogaster

Alignment Length:	442	Identity:	97/442 - (21%)
Similarity:	169/442 - (38%)	Gaps:	122/442 - (27%)

- Green bases have known domain annotations that are detailed below.

Frog   229 VLFMVFWLV--LFALQIYTYFSTRDQPTSRERLLFLFLTSIAECCSTPYSLLGLVFTV------- 284
            |:::.|:::  :|...:...|....:....|.||..|..::.|.|        |.|||
  Fly    43 VIYIQFFVIVFMFGKLLSKIFLGTLRAAEFEHLLERFWYALTETC--------LAFTVFRDDFNP 99

Frog   285 SFVALGVLTLCKFYLQGYRAFMNDPAMNRGMTEGVTLLILAVQTGLIELQVVHRAFLLSIILFIV 349
            .||||..:.|   :|:.:.....:                       .:..:.|:.:|..:..|.
  Fly   100 RFVALFTVLL---FLKSFHWLAEE-----------------------RVDFMERSPVLGWLFHIR 138

Frog   350 VASILQSMLEIADPIVLALGASRDKSLWKHFRAVSLCLFLLVFPSYMAYMI----CQF-FHMDFW 409
            |.|:| ::|.|.|                         ::|:..:|.:.::    .|. |..::.
  Fly   139 VGSLL-TVLGILD-------------------------YVLLIHAYNSTLVRGPTVQLVFGFEYA 177

Frog   410 LLIIISSSILTSLQVLGTLFIYVLFMIEEFRKEPVENMDDVIYY---VNGTYRLLEFLVALCVVA 471
            :|:.:.:|         |...|||...|.....|.||....:.|   |.|..:::.:::.:.::|
  Fly   178 ILLTVIAS---------TAIKYVLHAAEMRTDTPWENKAVFLLYTELVIGLIKVVLYILFVVIMA 233

Frog   472 --YGVSETVFGEWTVMGSMIIFIHSYYNVWLRAQLGWKSFLLRRDAVNKIKSL-PVATKEQLEQH 533
              |.:...||      ..|...|.::     |..|  ...::.|.|:..:.:| |.||.|:|.|.
  Fly   234 KIYALPMFVF------RPMFFTIRNF-----RKAL--NDVIMSRRAIRNMNTLYPDATPEELRQS 285

Frog   534 NDICSICYQDM-NSAVITPCSHFFHPGCLKKWLYVQETCPLCHCQL------KSLSQQATGE--- 588
            ::||.||.:|| |.:...||.|.||..||:.|...|:|||.|...:      .|.:....|:
  Fly   286 DNICIICREDMVNHSKKLPCGHIFHTTCLRSWFQRQQTCPTCRLNILRTPTVNSTAMPRQGDEAV 350

Frog   589 SGSSTNPVSEQSATNPPLGPVSRAEVTTEPLAAVPTRSALEQEPTMDIKVSG 640
            :.::.||:...:...|..|....|     |.|.|....|     ..|:.|:|
  Fly   351 AAAAGNPIPAAAGVQPAGGVPPPA-----PTAVVDGNQA-----RADVNVAG 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rnf145	NP_001072260.1	TRC8_N	8..506	CDD:372682	54/295 (18%)
		RING-H2_RNF145	533..575	CDD:319598	19/42 (45%)
		rad18	537..>651	CDD:273165	33/114 (29%)
		RING-H2 finger (C3H2C3-type)	537..574	CDD:319598	18/37 (49%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	585..610		5/27 (19%)
sip3	NP_001263152.1	HRD1	20..>365	CDD:227568	87/403 (22%)
sip3	NP_001263152.1	zf-RING_2	287..328	CDD:290367	19/40 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D897451at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920