DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rnf145 and Wdr62

DIOPT Version :9

Sequence 1:	NP_001072260.1	Gene:	rnf145 / 779713	XenbaseID:	XB-GENE-979193	Length:	695	Species:	Xenopus tropicalis
Sequence 2:	NP_001259886.1	Gene:	Wdr62 / 33367	FlyBaseID:	FBgn0031374	Length:	2397	Species:	Drosophila melanogaster

Alignment Length:	101	Identity:	30/101 - (29%)
Similarity:	47/101 - (46%)	Gaps:	20/101 - (19%)

- Green bases have known domain annotations that are detailed below.

Frog   578 LKSLSQQATGESGSSTNPVSEQSATNPP-----LGPVSRAEVTTEPLAAVPTRSALEQE-PTMDI 636
            ||.:|:..|.||......|.::   |.|     ...||:.:.|.   :|...|.|.|:| |.|::
  Fly  1799 LKKVSRFDTSESSRRATSVRQK---NRPKISVRFNTVSQIKYTP---SAKRERQAREEEPPEMEV 1857

Frog   637 KVSGSVEKRIGE--LEAHFSQGEANLNSNEVLQRLQ 670
               ||:....||  .|.:|::   |.|:.|.|:.:|
  Fly  1858 ---GSLPSDYGERSFEMYFAE---NGNAPENLENMQ 1887

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rnf145	NP_001072260.1	TRC8_N	8..506	CDD:372682
		RING-H2_RNF145	533..575	CDD:319598
		rad18	537..>651	CDD:273165	23/80 (29%)
		RING-H2 finger (C3H2C3-type)	537..574	CDD:319598
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	585..610		6/29 (21%)
Wdr62	NP_001259886.1	WD40	73..448	CDD:295369
		WD40 repeat	73..107	CDD:293791
		WD40 repeat	113..161	CDD:293791
		WD40	158..574	CDD:225201
		WD40 repeat	167..207	CDD:293791
		WD40 repeat	209..285	CDD:293791
		WD40 repeat	254..294	CDD:293791
		WD40 repeat	303..338	CDD:293791
		WD40 repeat	353..407	CDD:293791
		WD40	385..747	CDD:225201
		WD40	436..748	CDD:295369
		WD40 repeat	505..540	CDD:293791
		WD40 repeat	546..586	CDD:293791
		WD40 repeat	591..631	CDD:293791
		WD40 repeat	637..672	CDD:293791
		WD40 repeat	679..717	CDD:293791
		WD40 repeat	723..749	CDD:293791
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1408
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.860