Protein Alignment rnf145 and rnf-145

DIOPT Version :10

• Sequence 1: NP_001072260.1
• Gene: rnf145 / 779713
• XenbaseID: XB-GENE-979193
• Length: 695
• Species: Xenopus tropicalis
• Sequence 2: NP_491382.2
• Gene: rnf-145 / 172053
• WormBaseID: WBGene00022471
• Length: 742
• Species: Caenorhabditis elegans
• Alignment Length: 649
• Identity: 183/649 - (28%)
• Similarity: 331/649 - (51%)
• Gaps: 56/649 - (8%)

 Frog     4 KEKLEAMLNVALRVPSIMLLDVLYRWDVSSFFKQIQRSSLNNNPLFQY---------------KY 53
            ||....:|...||:|.::.:::|:|:...| |:.|....:...||..:               .:
 Worm    45 KEMSIMVLETGLRLPGLLFIELLWRYQGFS-FEDISDDMMKQTPLSYFDIPTMLDFVHRRNFDHH 108

 Frog    54 LALNMHYVGYILSVVLLTLPRQHLAKLYLYFVAALLLYAGHQISRDYVRSELESGYEGPMHIEPL 118
            .|:.:.|....:|::.||||...|.::|.:|::..|....:::|..||..|:::| |..:.::.|
 Worm   109 AAIILSYFVIFISLMFLTLPLSRLIRMYSHFLSVFLFGVAYKLSAIYVDLEMKTG-EEELKLDGL 172

 Frog   119 -SMNRFITALVGQLVVCTLCSCVMKTK-QIW--LFSAHMLPLLARLCLVPIETIVVINKFA---- 175
             .:.|.....:.|:::..|.|.:::.. :.|  ......||::||:|..|::.:...:.:|
 Worm   173 IKLERHGFHFLAQMLLVVLQSMLLEVDGEPWRVALPVFALPIVARMCGCPMDKLKNAHNYACTGT 237

 Frog   176 MIFTGLEVLYFLASNLLVPFNLAKSAYRELAQVVEVYGLLALGMS-LWNQLVVPVLFMVFWLVLF 239
            |||....:|| .|.:|:   ...|:|.|::..|..|:| ||.|:: ||.:|.:..|....|:.:|
 Worm   238 MIFIATYMLY-RAPSLI---KSTKTALRQIKAVFMVHG-LADGVAVLWRKLRILELLTFTWITMF 297

 Frog   240 ALQIYTYFSTRDQPTSR-ERLLFLFLTSIAECCSTPYSLLGLVFTVSFVALGVLTLCKFYLQGYR 303
            .:.:|.....:.:..|. .|:|   ||.:||..:||.:|..|..:||:|...:..|.|....|.|
 Worm   298 LMVLYVELIDKGRTWSEVGRIL---LTGVAETTNTPITLAALAVSVSYVCKWIADLTKLITGGTR 359

 Frog   304 AFMNDPAMNRGMTEGVTLLILAVQTGLIELQVVHRAFLLSIILFIVVASILQSMLEIADPIVLAL 368
            :..:..| :.|.||.|:::||.:|||.:.:||..:..||:::|:||::::|||:.||.:.::|.|
 Worm   360 SHGHVLA-HSGYTEAVSVVILCIQTGFLGMQVEQKTILLALVLYIVISALLQSLFEIIEVVLLNL 423

 Frog   369 GASRDKSLWKHFRAVSLCLFLLVFPSYMAYMICQFFHMDFWLLIIISSSILTSLQVLGTLFIYVL 433
            .:|...|..:|.|.:.:.|.|:|.|.:....:.....:|.:..|||::|...:.:.:|.:..|::
 Worm   424 PSSPTASRARHARCICIALLLVVIPFFTTKTMLALLPIDIYTAIIIANSATVTARAIGVILKYIV 488

 Frog   434 FMIEEFRKEPVENMDDVIYYVNGTYRLLEFLVALCVVAYGVSETVFGEWTVMGSMIIFIHSYYNV 498
            .::|...:||.|.:||:.||::...:.:|.|.|..|:.:|..:.|...::.....|:..|...|:
 Worm   489 LIVETKSEEPWEGIDDLTYYIDCANKGIELLAAKVVMVFGCMQVVKVGFSFATFAILLFHVIVNI 553

 Frog   499 WLRAQLGWKSFLLRRD-AVNKIKSLPVATKEQLEQHNDICSICYQDM-NSAVITPCSHFFHPGCL 561
            :.|.: ...||:..|: ||..|..|..|...||.:..|:|:||:.:| ..|.||||.|:||..||
 Worm   554 YKRLE-HTVSFIKNRNAAVKNINRLSKADVVQLREREDVCAICFIEMKEEARITPCKHYFHGPCL 617

 Frog   562 KKWLYVQETCPLCHCQLK------------SLSQQATGESGSST-----NPVSEQSATNPPLGP 608
            :|||.|:..||||:..:|            :|::....|.|::.     ||..:..|.|....|
 Worm   618 RKWLAVKMVCPLCYTYMKEDDFDSKSSSSGTLNEVQQNEEGAAVEENPENPEEQPEAPNAERAP 681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rnf145	NP_001072260.1	TRC8_N	8..506	CDD:463960	139/522 (27%)
		RING-H2_RNF145	533..575	CDD:319598	22/42 (52%)
		rad18	537..>651	CDD:273165	31/90 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	585..610		7/29 (24%)
rnf-145	NP_491382.2	TRC8_N	49..556	CDD:463960	138/517 (27%)
		RING-H2_RNF139-like	590..631	CDD:438139	22/40 (55%)