Protein Alignment SLC30A4 and ZnT63C

DIOPT Version :10

• Sequence 1: NP_037441.2
• Gene: SLC30A4 / 7782
• HGNCID: 11015
• Length: 429
• Species: Homo sapiens
• Sequence 2: NP_001261364.1
• Gene: ZnT63C / 38407
• FlyBaseID: FBgn0035432
• Length: 545
• Species: Drosophila melanogaster
• Alignment Length: 342
• Identity: 96/342 - (28%)
• Similarity: 172/342 - (50%)
• Gaps: 57/342 - (16%)

Human   111 KARLTIAAVLYLLFMIGELVGGYIANSLAIMTDALHMLTDLSAIILTLLALWLSSKSPTKRFTFG 175
            |.||.....|...|...|::.||:.||:|::.|:.|||.|::|::::.|::.:|.|..:|. |||
  Fly     8 KCRLLSMMWLTAFFFFVEIIVGYVTNSMALVADSFHMLGDIAALVISFLSVKMSPKKWSKN-TFG 71

Human   176 FHRLEVLSAMISVLLVYILMGFLLYEAVQRTIHMNYEINGDIMLITAAVGVAVNVIMGFLLNQSG 240
            :.|.|||.|:::.:.:..|...:..||.:|.|........::::|..|:|:.||||...||.:.|
  Fly    72 WARAEVLGALVNAVFLVALCFSITIEACKRFIEEEPIHEPELLVIVGALGLLVNVIGLCLLYEHG 136

Human   241 HRHSHSHSLPSNSPTRGSGCERNH-----------GQD--------------------------- 267
            ..|.|||         |.|..|||           |:|
  Fly   137 GHHGHSH---------GGGLTRNHSRLTELANMDEGEDEQNDFAYEKQKEKAPVKKSSHGHSHDP 192

Human   268 -SLAVRAAFVHALGDLVQSVGVLIAAYIIRFKPEYK---IADPICTYVFSLLVAFTTFRIIWDTV 328
             .:.:|.||:|.|.|.:.|:.|:|:|.:: :|.|:|   ..||..:.|..:|:..:.:.::.::.
  Fly   193 GQMNMRGAFLHVLSDALGSIIVVISAVVV-WKTEWKYRYYMDPALSIVLVVLILHSVWPLLRESA 256

Human   329 VIILEGVPSHLNVDYIKEALM-KIEDVYSVEDLNIWSLTSGKSTAIVHIQLIPGSSSKWEEVQSK 392
            :|:|:.||:|:.||.|::.|: |::.|.:|.:.::|.|...:..|..||:.  .:.|::.::..|
  Fly   257 LILLQTVPTHIQVDAIQKRLLEKVDGVLAVHEFHVWQLAGDRIIASAHIRC--RNLSEYMKIAEK 319

Human   393 ANHLLLNTFGMYRCTIQ 409
            ......|. |::..|||
  Fly   320 VKEFFHNE-GIHSTTIQ 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC30A4	NP_037441.2	CDF	123..413	CDD:273544	92/330 (28%)
		Zinc binding. /evidence=ECO:0000250|UniProtKB:O55174	240..264		8/23 (35%)
ZnT63C	NP_001261364.1	CzcD	10..340	CDD:440843	95/340 (28%)