Protein Alignment SLC30A4 and cdf-2

DIOPT Version :10

• Sequence 1: NP_037441.2
• Gene: SLC30A4 / 7782
• HGNCID: 11015
• Length: 429
• Species: Homo sapiens
• Sequence 2: NP_510091.2
• Gene: cdf-2 / 188574
• WormBaseID: WBGene00011821
• Length: 360
• Species: Caenorhabditis elegans
• Alignment Length: 342
• Identity: 136/342 - (39%)
• Similarity: 206/342 - (60%)
• Gaps: 31/342 - (9%)

Human    91 KVDSCDNCSKQREILKQRKVKARLTIAAVLYLLFMIGELVGGYIANSLAIMTDALHMLTDLSAII 155
            :.||.|:..      ..|:....|.:..||.|.||:.|::||.:|.||||:|||.|:|||.::::
 Worm    37 EADSTDSHD------SNRRATRILWLTVVLCLFFMVCEVIGGVLAGSLAIVTDAAHLLTDFASVL 95

Human   156 LTLLALWLSSKSPTKRFTFGFHRLEVLSAMISVLLVYILMGFLLYEAVQRTIHMNYEINGDIMLI 220
            ::|.:|:::.:.|:::.:|||||.|||.|..||.|::|:.|.|:..|:.|.:..:||:.|.||.:
 Worm    96 ISLFSLYIARRPPSQKMSFGFHRAEVLGAFFSVFLIWIVTGVLVVLAIMRIVSGDYEVEGGIMAL 160

Human   221 TAAVGVAVNVIMGFLLNQSGHRHSHSHSLPSNSPTRGSGCERNHGQ-----DSLAVRAAFVHALG 280
            |||:||.||::|..||...||.|||           |.|....|..     |::.|||||:|.||
 Worm   161 TAALGVVVNLVMLALLYFGGHSHSH-----------GGGSSHGHSHGGGNGDNINVRAAFIHVLG 214

Human   281 DLVQSVGVLIAAYIIRFKPEYKIADPICTYVFSLLVAFTTFRIIWDTVVIILEGVPSHLNVDYIK 345
            ||:||:|||:||..|.|:|.:.|.|||||.|||::|..||..|:.|.::::|||.||  |:|:.|
 Worm   215 DLLQSLGVLVAALFIYFQPSWVIIDPICTLVFSVIVLCTTIYILRDAMIVLLEGRPS--NIDFAK 277

Human   346 --EALMKIEDVYSVEDLNIWSLTSGKSTAIVHIQLIPGSSSKWEEVQSKANHLLLNTFGMYRCTI 408
              .:|..||.|..|.||.|||||..|....||:::...|.|  :.:..:...:|..|:.::..||
 Worm   278 VFSSLEDIEGVKKVHDLRIWSLTMDKIALSVHLEIDANSQS--QSILRETRKMLKQTYNVHEITI 340

Human   409 QLQSYRQEVDRT-CANC 424
            |::.:  ..:|: |..|
 Worm   341 QIEEF--GANRSDCGKC 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC30A4	NP_037441.2	CDF	123..413	CDD:273544	125/296 (42%)
		Zinc binding. /evidence=ECO:0000250|UniProtKB:O55174	240..264		7/23 (30%)
cdf-2	NP_510091.2	CzcD	33..343	CDD:440843	133/326 (41%)