Protein Alignment SLC30A2 and ZnT63C

DIOPT Version :9

• Sequence 1: NP_001004434.1
• Gene: SLC30A2 / 7780
• HGNCID: 11013
• Length: 372
• Species: Homo sapiens
• Sequence 2: NP_001261364.1
• Gene: ZnT63C / 38407
• FlyBaseID: FBgn0035432
• Length: 545
• Species: Drosophila melanogaster
• Alignment Length: 356
• Identity: 103/356 - (28%)
• Similarity: 177/356 - (49%)
• Gaps: 62/356 - (17%)

Human    68 GKAQRQLYVASAICLLFMIGEVVGGYLAHSLAVMTDAAHLLTDFASMLISLFSLWMSSRPATKTM 132
            ||..|.|.:.......|.: |::.||:.:|:|::.|:.|:|.|.|:::||..|:.||.:..:|.
  Fly     6 GKKCRLLSMMWLTAFFFFV-EIIVGYVTNSMALVADSFHMLGDIAALVISFLSVKMSPKKWSKN- 68

Human   133 NFGWQRAEILGALVSVLSIWVVTGVLVYLAVERLISGDYEIDGGTMLITSGCAVAVNIIMGLTL- 196
            .|||.|||:|||||:.:.:..:...:...|.:|.|..:...:...::|.....:.||:| ||.|
  Fly    69 TFGWARAEVLGALVNAVFLVALCFSITIEACKRFIEEEPIHEPELLVIVGALGLLVNVI-GLCLL 132

Human   197 --HQSGHGHSHG---TTN------------------------QQEENP---------------SV 217
              |...||||||   |.|                        |:|:.|               ::
  Fly   133 YEHGGHHGHSHGGGLTRNHSRLTELANMDEGEDEQNDFAYEKQKEKAPVKKSSHGHSHDPGQMNM 197

Human   218 RAAFIHVIGDFMQSMGVLVAAYILYFKPEYK---YVDPICTFVFSILVLGTTLTILRDVILVLME 279
            |.||:||:.|.:.|:.|:::|.::: |.|:|   |:||..:.|..:|:|.:...:||:..|:|::
  Fly   198 RGAFLHVLSDALGSIIVVISAVVVW-KTEWKYRYYMDPALSIVLVVLILHSVWPLLRESALILLQ 261

Human   280 GTPKGVDFTAVRDLLL-SVEGVEALHSLHIWALTVAQPVLSVHIAIAQNTDAQAVLKTASSRLQG 343
            ..|..:...|::..|| .|:||.|:|..|:|.|...:.:.|.||.....::...:    :.:::.
  Fly   262 TVPTHIQVDAIQKRLLEKVDGVLAVHEFHVWQLAGDRIIASAHIRCRNLSEYMKI----AEKVKE 322

Human   344 KFH---FHTVTIQIEDYSEDMKDCQACQGPS 371
            .||   .|:.|||.| :|| ::.|....|.|
  Fly   323 FFHNEGIHSTTIQPE-FSE-IEGCNMSDGTS 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC30A2	NP_001004434.1	CDF	83..357	CDD:273544	94/325 (29%)
		Cation_efflux	83..278	CDD:279834	71/242 (29%)
ZnT63C	NP_001261364.1	CzcD	10..339	CDD:224151	96/337 (28%)
		Cation_efflux	21..260	CDD:279834	71/242 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1230
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810