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Protein Alignment SLC30A2 and ZnT35C

DIOPT Version :10

Sequence 1:	NP_001004434.1	Gene:	SLC30A2 / 7780	HGNCID:	11013	Length:	372	Species:	Homo sapiens
Sequence 2:	NP_609741.3	Gene:	ZnT35C / 34890	FlyBaseID:	FBgn0028516	Length:	472	Species:	Drosophila melanogaster

Alignment Length:	454	Identity:	187/454 - (41%)
Similarity:	256/454 - (56%)	Gaps:	103/454 - (22%)

- Green bases have known domain annotations that are detailed below.

Human     8 HLLD-ARPAIRSYTGSLWQEGAGWIPLPRPGLDLQAIELAAQSNH-----HCH--AQKGPDSHCD 64
            ||:: .:|.:....|:    |....| ..|....|...|..:||:     |||  ..:|.|.
  Fly    29 HLMEQGQPGVNVVAGN----GNNNHP-ATPATPAQIFCLHGRSNNVEVRDHCHRARSEGVDV--- 85

Human    65 PKKGKAQRQLYVASAICLLFMIGEVVGGYLAHSLAVMTDAAHLLTDFASMLISLFSLWMSSRPAT 129
                ||:|:|.:||.:||:|||.|:|||.|::|||:.||||||||||||.:||||::|::.||:|
  Fly    86 ----KARRKLIIASILCLVFMIAEIVGGVLSNSLAIATDAAHLLTDFASFMISLFAIWIAGRPST 146

Human   130 KTMNFGWQRAEILGALVSVLSIWVVTGVLVYLAVERLISGDYEIDGGTMLITSGCAVAVNIIMGL 194
            :.|:|||.|||::||:.||..|||:||:||:||:.||||||||::...||||||.|:.||:|||:
  Fly   147 QRMSFGWYRAEVIGAMASVFMIWVITGILVWLAIGRLISGDYEVNAKIMLITSGLAILVNVIMGV 211

Human   195 TLHQ-------SGHGHSHG----------TTNQQEENPS-------------------------- 216
            .|..       .|||||||          |:....::||
  Fly   212 QLQHGHSHGLGGGHGHSHGGSKNASHVQATSTPCSDSPSQRIEGGVAYAPEDAELPGGGLPTFSY 276

Human   217 ----------------------------------------VRAAFIHVIGDFMQSMGVLVAAYIL 241
                                                    ||||.||||||.:||:||.|||.::
  Fly   277 QNTKLVDPTLDLEIAAVLAETAPGSHHHGGPVGREAVNMNVRAALIHVIGDVIQSVGVFVAAGVI 341

Human   242 YFKPEYKYVDPICTFVFSILVLGTTLTILRDVILVLMEGTPKGVDFTAVRDLLLSVEGVEALHSL 306
            ||.|||..|||||||||||:||.||.||::|.:||||||||..:.:..|..:...:||||.:|:|
  Fly   342 YFWPEYSIVDPICTFVFSIIVLFTTFTIMKDALLVLMEGTPNYMHYAEVLQIFQGIEGVERVHNL 406

Human   307 HIWALTVAQPVLSVHIAIAQNTDAQAVLKTASSRLQGKFHFHTVTIQIEDYSEDMKDCQACQGP 370
            .||||::.:..||.|:|||:|.:.:.:|..|:|.:..:::|...|||||||:..|:.|..|..|
  Fly   407 RIWALSINKVALSAHLAIAENANPKRILDAATSAVHLRYNFFETTIQIEDYTAQMESCLQCNVP 470

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.