Protein Alignment SLC30A1 and ZnT86D

DIOPT Version :10

• Sequence 1: NP_067017.2
• Gene: SLC30A1 / 7779
• HGNCID: 11012
• Length: 507
• Species: Homo sapiens
• Sequence 2: NP_650049.1
• Gene: ZnT86D / 41342
• FlyBaseID: FBgn0037875
• Length: 366
• Species: Drosophila melanogaster
• Alignment Length: 423
• Identity: 120/423 - (28%)
• Similarity: 181/423 - (42%)
• Gaps: 95/423 - (22%)

Human     6 RNRGRLLCMLALTFMFMVLEVVVSRVTSSLAMLSDSFHMLSDVLALVVALVAERFARRTHATQKN 70
            ||...|...|.|...|..:|:....||:||.::||||||..|...|:..|.|. ...:..|..|.
  Fly    31 RNSRNLFLFLLLNLSFAFVELFYGIVTNSLGLISDSFHMFFDCTGLLAGLAAS-VITKWKANDKF 94

Human    71 TFGWIRAEVMGALVNAIFLTGLCFAILLEAIERFIEPHEMQQPLVVLGVGVAGLLVNVLGLCLFH 135
            ::|::||||:...||::||..:.|.||.|.:||.|||.|::...:.: |.|.|||||::|:..|:
  Fly    95 SYGYVRAEVLAGFVNSLFLLFIAFFILSEGVERLIEPPEVKHERLFV-VSVLGLLVNLVGIYAFN 158

Human   136 HHSGFSQDSGHGHSHGGHGHGHGLPKGPRVKSTRPGSSDINVAPGEQGPDQEETNTLVANTSNSN 200
            |       .|||||||||||.||                     |..|......:|...| .|..
  Fly   159 H-------GGHGHSHGGHGHSHG---------------------GGHGHGHSHGHTDAGN-HNHQ 194

Human   201 GLKLDPADPENPRSGDTVEVQVNGNLVREPDHMELEEDRAGQLN--MRGVFLHVLGDALGSVIVV 263
            .:.||..               :|:......|.....|.:|..:  |||||||:|.|.||||.|:
  Fly   195 AITLDNG---------------HGHSHDHDSHGHSHGDMSGSNSQIMRGVFLHILADTLGSVGVI 244

Human   264 VNALVFY-FSWKGCSEGDFCVNPCFPDPCKAFVEIINSTHASVYEAGPCWVLYLDPTLCVVMVCI 327
            ::|::.: |.|                                        :..|| :|.:.:.:
  Fly   245 ISAVLMHMFGW----------------------------------------MIADP-ICSIFIAL 268

Human   328 LL-YTTYPLLKESALILLQTVPKQIDIRNL---IKELRNVEGVEEVHELHVWQLAGSRIIATAHI 388
            |: .:...|:|||.:||:|..|..:| |:|   .:::..:.||..|.|.|.|.|.....:....:
  Fly   269 LIALSVLSLIKESIMILMQRQPADLD-RSLPQCYQKVTGLAGVYAVQEPHFWTLCSDVYVGALKL 332

Human   389 KCEDPTSYMEVAKTIKDVFHNHGIHATTIQPEF 421
            :.........|....:.:|...|:....||.::
  Fly   333 EVSKNVDPKYVVTHTRMIFEAVGVKQIYIQLDY 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC30A1	NP_067017.2	CzcD	5..420	CDD:440843	120/420 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	142..217		20/74 (27%)
		6 X 2 AA approximate repeats of H-G	146..158		10/11 (91%)
ZnT86D	NP_650049.1	CzcD	45..365	CDD:440843	115/407 (28%)