Protein Alignment RNF112 and Rnf112

DIOPT Version :9

• Sequence 1: XP_006721634.1
• Gene: RNF112 / 7732
• HGNCID: 12968
• Length: 639
• Species: Homo sapiens
• Sequence 2: NP_619516.1
• Gene: Rnf112 / 24916
• RGDID: 3986
• Length: 631
• Species: Rattus norvegicus
• Alignment Length: 640
• Identity: 560/640 - (87%)
• Similarity: 591/640 - (92%)
• Gaps: 10/640 - (1%)

Human     1 MPRPALSVTSFCHRLGKRERKQSFMGNSGNSWSHTPFPKLELGLGPQPMAPRELPTCSICLERLR 65
            ||||.||||:|||||||||.|:||||||.|||||..|||||||||.:|..|||.|||||||||||
  Rat     1 MPRPVLSVTAFCHRLGKRESKRSFMGNSSNSWSHASFPKLELGLGQRPSPPRESPTCSICLERLR 65

Human    66 DPISLDCGHDFCIRCFSTHRLPGCEPPCCPECRKICKQKRGLRSLGEKMKLLPQRPLPPALQETC 130
            :|||||||||||||||||||:||||.|||||||||||||:|||||||:|||||||||||||||||
  Rat    66 EPISLDCGHDFCIRCFSTHRIPGCELPCCPECRKICKQKKGLRSLGERMKLLPQRPLPPALQETC 130

Human   131 PVRAEPLLLVRINASGGLILRMGAINRCLKHPLARDTPVCLLAVLGEQHSGKSFLLNHLLQGLPG 195
            .||||.||||||||||||||||||||||||||||||||||||||||||||||||||:|||:||||
  Rat   131 AVRAERLLLVRINASGGLILRMGAINRCLKHPLARDTPVCLLAVLGEQHSGKSFLLDHLLRGLPG 195

Human   196 LESGEGGRPRGGEASLQGCRWGANGLARGIWMWSHPFLLGKEGKKVAVFLVDTGDAMSPELSRET 260
            ||||:..||| .|.||.|.|||||||.||||||||||||||||||||||||||||.|||||||||
  Rat   196 LESGDSTRPR-AEGSLPGIRWGANGLTRGIWMWSHPFLLGKEGKKVAVFLVDTGDVMSPELSRET 259

Human   261 RIKLCALTTMLSSYQILSTSQELKDTDLDYLEMFVHVAEVMGKHYGMVPIQHLDLLVRDSSHPNK 325
            |:||||||.||||||||:||||||||||.|||||||||||||||||||||||||||||||||.||
  Rat   260 RVKLCALTMMLSSYQILNTSQELKDTDLGYLEMFVHVAEVMGKHYGMVPIQHLDLLVRDSSHHNK 324

Human   326 AGQGHVGNIFQSTPLAASQRLSGRYPKVQELLQGKRARCCLLPAPGRRRMNQGHASP-GDTDDDF 389
            :||||||:|.        |:|||:||||||||.||||||.|||||.|:.:|:|.||| |:|:|||
  Rat   325 SGQGHVGDIL--------QKLSGKYPKVQELLLGKRARCYLLPAPERQWVNKGQASPGGNTEDDF 381

Human   390 RHLLGAYVSDVLSAAPQHAKSRCQGYWNEGRAVARGDRRLLTGQQLAQEIKNLSGWMGRTGPGFT 454
            .|...||:|||||.|||||||||||||:||||:|||||||||||||||||||||||||::||.|:
  Rat   382 SHHFRAYISDVLSTAPQHAKSRCQGYWSEGRAMARGDRRLLTGQQLAQEIKNLSGWMGKSGPSFS 446

Human   455 SPDEMAAQLHDLRKVEAAKREFEEYVRQQDVATKRIFSALRVLPDTMRNLLSTQKDAILARHGVA 519
            |||||||||||||||||||:||||||||||:||||||||||||||||||||||||||||||||||
  Rat   447 SPDEMAAQLHDLRKVEAAKKEFEEYVRQQDIATKRIFSALRVLPDTMRNLLSTQKDAILARHGVA 511

Human   520 LLCKGRDQTLEALEAELQATAKAFMDSYTMRFCGHLAAVGGAVGAGLMGLAGGVVGAGMAAAALA 584
            ||||.|:||||||||||||.|||||||||||||||||||||||||||||||||||||||||||||
  Rat   512 LLCKEREQTLEALEAELQAEAKAFMDSYTMRFCGHLAAVGGAVGAGLMGLAGGVVGAGMAAAALA 576

Human   585 AEAGMVAAGAAVGATGAAVVGGGVGAGLAATVGCMEKEEDERLLEGDREPLLQEE 639
            ||||||||||||||||||||||||||||||||||||||||||:..||||||||||
  Rat   577 AEAGMVAAGAAVGATGAAVVGGGVGAGLAATVGCMEKEEDERVQGGDREPLLQEE 631

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RNF112	XP_006721634.1	RING	56..101	CDD:238093	41/44 (93%)
		GBP	163..402	CDD:206650	193/239 (81%)
Rnf112	NP_619516.1	RING	56..101	CDD:238093	41/44 (93%)
		Interaction with ZBTB16. /evidence=ECO:0000250|UniProtKB:Q96DY5	131..631		445/508 (88%)
		GBP	163..394	CDD:206650	193/239 (81%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83687730
Domainoid	1	1.000	526	1.000	Domainoid score	I6416
eggNOG	0	0.000	Not matched by this tool.
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5176
Inparanoid	1	1.050	1132	1.000	Inparanoid score	I4510
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG39698
OrthoDB	1	1.010	-	-		D187713at32523
OrthoFinder	1	1.000	-	-		FOG0006675
OrthoInspector	1	1.000	-	-		oto142474
orthoMCL	1	0.900	-	-		OOG6_117529
Panther	1	1.100	-	-	LDO	PTHR10751
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3792
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	16.410