Protein Alignment RNF112 and unm_sa911

DIOPT Version :10

• Sequence 1: XP_006721634.1
• Gene: RNF112 / 7732
• HGNCID: 12968
• Length: 639
• Species: Homo sapiens
• Sequence 2: XP_021323188.1
• Gene: unm_sa911 / 100334992
• ZFINID: ZDB-GENE-120727-3
• Length: 629
• Species: Danio rerio
• Alignment Length: 571
• Identity: 104/571 - (18%)
• Similarity: 177/571 - (30%)
• Gaps: 222/571 - (38%)

Human   136 PLLLVRINASGGLILRMGAINRCLKHPLARDTPVCLLAVLGEQHSGKSFLLNHLLQGLPGLESGE 200
            |:.|:...:.|.|.::..|: :.|:.   ...||.::||:|...:|||:|||.|.....|...|.
Zfish     4 PVCLIDTASDGKLCVQPAAL-QILQQ---IQQPVVVVAVVGLYRTGKSYLLNRLAGKHSGFALGS 64

Human   201 GGRPRGGEASLQGCRWGANGLARGIWMW--SHP-------FLLGKEGKKVAVFLVDTGDAMSPEL 256
                            ......:|||||  .||       .||..||    :..||.||:....
Zfish    65 ----------------TVESKTKGIWMWCVPHPTKAETTLLLLDTEG----LGDVDKGDSRHDS- 108

Human   257 SRETRIKLCALTTMLSSYQILST------------------------------------------ 279
                  .:.:|..:|||..:.::
Zfish   109 ------NIFSLAVLLSSTLVFNSRGTIDNKAIEELQYVTELTECIKVKSPNEDVDNSTEFVKFFP 167

Human   280 ---------SQELK-----DTDLDYLEMFVHVAEVMGKHYGMVPIQHLDLLVRDSSHPNKAGQGH 330
                     |.|||     .|:..|||..:.:     ||.....:...:|       |.:.
Zfish   168 SFIWAVRDFSLELKIDGEDATEDQYLEFALKL-----KHGTSKKVMEFNL-------PREC---- 216

Human   331 VGNIFQS------------TPLAASQRL--SGRYPKVQELLQGKRARCCLLPAPGRRRMNQGHAS 381
            :.|.|.|            ..::..:||  :...|:.||:  .||...|:......:|:..||..
Zfish   217 IKNFFPSRTCFTFPFPTTLEKMSTLERLGPADLCPEFQEV--SKRFCTCVYEKSEVKRLKDGHTV 279

Human   382 PGDTDDDFRHLLGAYVSDVLSAA------------------------------------------ 404
            .|..   ..||...||:.:.|.|
Zfish   280 TGRV---LGHLAELYVNTISSGAVPCLENAVVALAQIENQAALQEALQVYQVGMEEKKRAFPLEL 341

Human   405 ----PQH---AKSRCQGYW-----------------------------NEGRAVARGDRRLLTGQ 433
                .:|   ::|..|.:.                             |:..:|.:.:..||:..
Zfish   342 EQVSAEHQRLSQSATQTFMAESFRDTDGKHLKALEEEINKLFDACLRENDQASVKKCENLLLSLS 406

Human   434 QLAQEIKNLSGWMGRTGPGFTSPDEMAAQLHDL--------RKVEAAKREFEEYVRQQDVATKRI 490
            ....| |:..|:..:.| |:   |.....|.|:        :|...|:...:|:::.:.|.:|.|
Zfish   407 ATMTE-KHKQGFYAKPG-GY---DVFCRDLEDIVKKYNSLVKKEVKAEVVLQEFLKLKSVDSKAI 466

Human   491 FSALRVLPDTMRNLLSTQKDAILARHGVALLCKGRDQTLEALEAELQATAK 541
            ..|.|.|.:..:.:....:.|:|....|....:.:.|..|.:|.|.::.|:
Zfish   467 LQADRKLSEKEKKIKEETERAVLLEQEVKAKEETQRQLKERMEVEQRSNAE 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RNF112	XP_006721634.1	RING-HC_RNF112	53..104	CDD:438200
		GBP	163..402	CDD:206650	64/317 (20%)
unm_sa911	XP_021323188.1	GBP	40..273	CDD:460516	52/277 (19%)
		GBP_C	281..571	CDD:293879	39/245 (16%)
		coiled coil	540..551	CDD:293879
		coiled coil	560..571	CDD:293879